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一项关于重复经颅磁刺激治疗难治性幻听对皮质激活影响的初步功能磁共振成像研究。

A preliminary fMRI study of the effects on cortical activation of the treatment of refractory auditory hallucinations with rTMS.

作者信息

Fitzgerald Paul B, Sritharan Anusha, Benitez Jessica, Daskalakis Z Jeff, Jackson Graeme, Kulkarni Jayashri, Egan Gary F

机构信息

Alfred Psychiatry Research Centre, The Alfred and Monash University Department of Psychological Medicine, Commercial Rd, Melbourne, Victoria 3004, Australia.

出版信息

Psychiatry Res. 2007 May 15;155(1):83-8. doi: 10.1016/j.pscychresns.2006.12.011. Epub 2007 Mar 29.

Abstract

Three patients underwent fMRI during a word generation task before and after successful treatment of auditory hallucinations with rTMS and were compared to four control subjects. There was a significant increase and more normal task related brain activation in brain areas involved in language processing including left temporoparietal cortex after rTMS treatment.

摘要

三名患者在接受重复经颅磁刺激(rTMS)成功治疗幻听前后,于单词生成任务期间接受了功能磁共振成像(fMRI)检查,并与四名对照受试者进行了比较。rTMS治疗后,包括左侧颞顶叶皮质在内的参与语言处理的脑区中,与任务相关的脑激活显著增加且更为正常。

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