[以颈面部蜂窝织炎为表现的皮肤淋巴瘤]
[Cervicofacial cellulitis revealing cutaneous lymphomas].
作者信息
Benbouzid M A, Bencheikh R, Benhammou A, El Edghiri H, Boulaich M, Essakali L, Kzadri M
机构信息
Service d'ORL et de chirurgie maxillofaciale, hôpital des spécialités, CHU Rabat-Salé, Maroc.
出版信息
Rev Stomatol Chir Maxillofac. 2007 Jun;108(3):228-30. doi: 10.1016/j.stomax.2006.11.005. Epub 2007 Mar 30.
INTRODUCTION
The cervicofacial localization of cutaneous lymphomas is rare. These lymphomas usually present as a long-lasting and treatment-refractory papule or nodule. Lymphomas can also be revealed by cervicofacial cellulitis.
CASES
We report 2 cases of cervicofacial cellulitis revealing a cutaneous lymphoma. The diagnosis was proved by multiple biopsies, performed because there was no clinical improvement in spite of an aggressive and adequate antibiotherapy. Our 2 patients were treated by radio and chemotherapy.
DISCUSSION
Cutaneous lymphomas are lymphocytic proliferations stemming from cutaneous lymphoid tissue, without nodal, medullary, or visceral localization. Their clinical presentation is quite polymorphic, and cellulitis is one of the modes of revelation, especially forehead and neck localization. They have no portal of entry and are resistant to treatment. The diagnosis relies on histology, and biopsies must be performed if there is a suspicion of lymphoma. The treatment is radio and chemotherapy, and the evolution depends on the tumoral stage.
引言
皮肤淋巴瘤的头颈部定位较为罕见。这些淋巴瘤通常表现为持久且难治的丘疹或结节。淋巴瘤也可能以头颈部蜂窝织炎为首发表现。
病例
我们报告2例以头颈部蜂窝织炎为首发表现的皮肤淋巴瘤。尽管进行了积极且充分的抗生素治疗，但临床症状无改善，因此通过多次活检确诊。我们的2例患者接受了放疗和化疗。
讨论
皮肤淋巴瘤是起源于皮肤淋巴组织的淋巴细胞增殖性疾病，无淋巴结、骨髓或内脏定位。其临床表现非常多样，蜂窝织炎是其中一种首发表现方式，尤其是在前额和颈部定位时。它们没有感染入口且对治疗有抵抗性。诊断依赖于组织学检查，如果怀疑淋巴瘤必须进行活检。治疗方法是放疗和化疗，病情发展取决于肿瘤分期。
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