Taylor David, Hazenberg Jan G, Lee T Clive
Trinity Centre for Bioengineering, Mechanical Engineering Department, Trinity College, Dublin 2, Ireland.
Nat Mater. 2007 Apr;6(4):263-8. doi: 10.1038/nmat1866.
Our bones are full of cracks, which form and grow as a result of daily loading activities. Bone is the major structural material in our bodies. Although weaker than many engineering materials, it has one trick that keeps it ahead - it can repair itself. Small cracks, which grow under cyclic stresses by the mechanism of fatigue, can be detected and removed before they become long enough to be dangerous. This article reviews the work that has been done to understand how cracks form and grow in bone, and how they can be detected and repaired in a timely manner. This is truly an interdisciplinary research field, requiring the close cooperation of materials scientists, biologists and engineers.
我们的骨骼布满了裂纹，这些裂纹是日常负荷活动的结果，会不断形成和扩大。骨骼是我们身体中的主要结构材料。尽管它比许多工程材料都要脆弱，但它有一个使其领先的窍门——它能够自我修复。在循环应力作用下通过疲劳机制生长的小裂纹，在其长得足够长而变得危险之前就能够被检测到并消除。本文回顾了为了解骨骼中裂纹如何形成和生长，以及如何及时检测和修复它们所开展的工作。这确实是一个跨学科的研究领域，需要材料科学家、生物学家和工程师的密切合作。
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