Department of Plant Genetics, The Weizmann Institute of Science, Rehovot, Israel.
Planta Med. 1981 Jul;42(7):236-43. doi: 10.1055/s-2007-971633.
Following previous results, which indicated that cell lines derived from different Mentha chemotypes were either capable or not capable to biotransform pulegone into isomenthone, we studied menthone biotransformation by in vitro cultured Mentha cell lines. All the six cell lines did transform (-)-menthone into another monoterpene. The latter was identified by GLC, TLC and NMR techniques as (+)-neomenthol. None of these cell lines reduced (+)-isomenthoneto the corresponding alcohol. These results indicate a stereospecificity in respect to both precursor and product in this plant cell biotransformation system.
继先前的研究结果表明，源自不同薄荷化学型的细胞系能够或不能将胡薄荷酮生物转化为异胡薄荷酮之后，我们研究了体外培养的薄荷细胞系对薄荷酮的生物转化。所有 6 种细胞系均将（-）-薄荷酮转化为另一种单萜。后者通过 GLC、TLC 和 NMR 技术鉴定为（+）-新薄荷醇。这些细胞系均未将（+）-异胡薄荷酮还原为相应的醇。这些结果表明在该植物细胞生物转化系统中，无论是前体还是产物都具有立体特异性。
