A possible mosaic form of delayed centromere separation and aneuploidy.
作者信息
Méhes K, Kosztolányi G
机构信息
Department of Paediatrics, University Medical School of Pécs, Hungary.
出版信息
Hum Genet. 1992 Feb;88(4):477-8. doi: 10.1007/BF00215686.
PMID:1740325
Abstract
On average, a "normal" centromere separation sequence was seen in 3 neonates with trisomy 18 and in their parents. When evaluating individual mitoses, unusually late separating chromosomes 18 were found in a few cells of one of the parents in each family. A possible germline mosaicism of delayed separation in the parent may account for trisomy in the offspring.
摘要
Zotero 插件