雷帕霉素靶蛋白与衰老：少即是多。

TOR and aging: less is more.

作者信息

Schieke Stefan M, Finkel Toren

机构信息

Cardiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Cell Metab. 2007 Apr;5(4):233-5. doi: 10.1016/j.cmet.2007.03.005.

DOI:10.1016/j.cmet.2007.03.005

PMID:17403368

Abstract

Metabolism and mitochondrial activity are thought to be important determinants of life span. A new study in this issue of Cell Metabolism (Bonawitz et al., 2007) suggests that the TOR pathway controls mitochondrial respiration in yeast and that the harder mitochondria work, the longer yeast live.

摘要

新陈代谢和线粒体活性被认为是寿命的重要决定因素。本期《细胞代谢》（博纳维茨等人，2007年）中的一项新研究表明，TOR信号通路控制酵母中的线粒体呼吸，并且线粒体工作越努力，酵母寿命就越长。