Suzuki Yasuo, Wakabayashi Takayuki, Saito Eiko, Suwa Akira
Tokai University School of Medicine, Department of Internal Medicine, Division of Rheumatology.
Clin Calcium. 2007 Apr;17(4):546-52.
From the results of recent randomized controlled clinical trials of disease modifying antirheumatic drugs (DMARDs), slowing radiographic progression has been documented with the use of methotrexate, leflunomide, salazusulfapyridine, IM gold, and cyclosporine. Although the effects of DMARDs is inferior to that of anti-tumor necrosis factor (TNF) agents, DMARDs can stop the progression of joint damage with the achievement of remission or good response.
从近期改善病情抗风湿药（DMARDs）的随机对照临床试验结果来看，已证明使用甲氨蝶呤、来氟米特、柳氮磺胺吡啶、注射用金制剂和环孢素可减缓影像学进展。尽管DMARDs的效果不如抗肿瘤坏死因子（TNF）药物，但DMARDs可通过实现病情缓解或良好反应来阻止关节损伤的进展。
