类风湿关节炎的影像学进展：三项对照试验的结果
Radiographic progression in rheumatoid arthritis: results of 3 comparative trials.
作者信息
van Riel P L, van der Heijde D M, Nuver-Zwart I H, van de Putte L B
机构信息
Department of Rheumatology, University Hospital Nijmegen, The Netherlands.
出版信息
J Rheumatol. 1995 Sep;22(9):1797-9.
In 3 clinical trials the effects of 6 different disease modifying antirheumatic drugs on radiographic progression were evaluated. Despite the wide range in disease duration of patients in the different studies, a statistically significant slowing of radiographic progression was found in those patients treated with aurothioglucose, sulfasalazine, and methotrexate compared to auranofin, hydroxychloroquine, and azathioprine, respectively. These drugs might therefore be considered as disease controlling antirheumatic drugs.
在3项临床试验中，评估了6种不同的改善病情抗风湿药物对影像学进展的影响。尽管不同研究中患者的病程差异很大，但与金诺芬、羟氯喹和硫唑嘌呤相比，接受金硫葡萄糖、柳氮磺胺吡啶和甲氨蝶呤治疗的患者在影像学进展方面有统计学意义的显著减缓。因此，这些药物可被视为控制疾病的抗风湿药物。
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