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Docetaxel-induced Meibomian duct inflammation and blockage leading to chalazion formation.

作者信息

Gupta S, Silliman C G, Trump D L

机构信息

Department of Medicine, School of Medicine and Biochemical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.

出版信息

Prostate Cancer Prostatic Dis. 2007;10(4):396-7. doi: 10.1038/sj.pcan.4500939. Epub 2007 Apr 3.

DOI:10.1038/sj.pcan.4500939
PMID:17404582
Abstract

We report a 71-year male with castration-resistant metastatic prostate cancer who was treated with weekly docetaxel for 12 weeks and developed significant eye irritation and dryness during treatment. Subsequently, the patient presented with a lower eyelid mass, which on excision was demonstrated to be a chalazion. Docetaxel induced Meibomian duct inflammation and blockage is the likely cause of this presentation in a patient with no history of eyelid masses in the past.

摘要

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Prostate Cancer Prostatic Dis. 2007;10(4):396-7. doi: 10.1038/sj.pcan.4500939. Epub 2007 Apr 3.
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The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland.睑板腺功能障碍国际研讨会:睑板腺解剖、生理及病理生理学小组委员会报告
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