Bomblies Kirsten, Weigel Detlef
Department of Molecular Biology, Max Planck Institute for Developmental Biology, Spemanstrasse 37-39, 72076 Tübingen, Germany.
Nat Rev Genet. 2007 May;8(5):382-93. doi: 10.1038/nrg2082. Epub 2007 Apr 3.
Ecological factors, hybrid sterility and differences in ploidy levels are well known for contributing to gene-flow barriers in plants. Another common postzygotic incompatibility, hybrid necrosis, has received comparatively little attention in the evolutionary genetics literature. Hybrid necrosis is associated with a suite of phenotypic characteristics that are similar to those elicited in response to various environmental stresses, including pathogen attack. The genetic architecture is generally simple, and complies with the Bateson-Dobzhansky-Muller model for hybrid incompatibility between species. We survey the extensive literature on this topic and present the hypothesis that hybrid necrosis can result from autoimmunity, perhaps as a pleiotropic effect of evolution of genes that are involved in pathogen response.
生态因素、杂种不育以及倍性水平差异是导致植物基因流动障碍的常见因素。另一种常见的合子后不相容性——杂种坏死，在进化遗传学文献中受到的关注相对较少。杂种坏死与一系列表型特征相关，这些特征类似于对各种环境胁迫（包括病原体攻击）做出反应时引发的特征。其遗传结构通常较为简单，符合物种间杂种不相容性的贝特森-多布赞斯基-穆勒模型。我们查阅了关于这一主题的大量文献，并提出假说：杂种坏死可能源于自身免疫，这或许是参与病原体反应的基因进化的一种多效性效应。
