Connelly Daniela, Veriava Youssef, Roberts Sue, Tsotetsi Josephine, Jordan Annie, DeSilva Eliot, Rosen Sydney, DeSilva Mary Bachman
Boston University School of Public Health, Center for International Health and Development, Boston, Massachusetts, USA.
S Afr Med J. 2007 Feb;97(2):115-20.
To determine the prevalence of HIV infection and the extent of disease progression based on CD4 count in a public health system workforce in southern Africa.
Cross-sectional voluntary, anonymous, unlinked survey including an oral fluid or blood sample and a brief demographic questionnaire.
Two public hospitals in Gauteng, South Africa.
All 2 032 professional and support staff employed by the two hospitals.
HIV prevalence and CD4 cell count distribution.
Overall prevalence of HIV was 11.5%. By occupation, prevalence was highest among student nurses (13.8%) and nurses (13.7%). The highest prevalence by age was in the 25 - 34-year group (15.9%). Nineteen per cent of HIV-positive participants who provided blood samples had CD4 counts less than or equal to 200 cells/ microl 28% had counts 201 - 350 cells/ microl, 18% had counts 351 - 500 cells/ microl, and 35% had counts above 500 cells/ microl.
One out of 7 nurses and nursing students in this public sector workforce was HIV-positive. A high proportion of health care workers had CD4 counts below 350 cells/ microl, and many were already eligible for antiretroviral therapy under South African treatment guidelines. Given the short supply of nurses in South Africa, knowledge of prevalence in this workforce and provision of effective AIDS treatment are crucial for meeting future staffing needs.
确定南部非洲公共卫生系统工作人员中艾滋病毒感染率以及基于CD4细胞计数的疾病进展程度。
横断面自愿、匿名、非关联调查，包括口腔液或血液样本以及简短的人口统计学调查问卷。
南非豪登省的两家公立医院。
这两家医院雇用的所有2032名专业和辅助工作人员。
艾滋病毒感染率和CD4细胞计数分布。
艾滋病毒总体感染率为11.5%。按职业划分，学生护士（13.8%）和护士（13.7%）中的感染率最高。按年龄划分，25至34岁年龄组的感染率最高（15.9%）。提供血液样本的艾滋病毒阳性参与者中，19%的CD4细胞计数小于或等于200个/微升，28%的计数为201 - 350个/微升，18%的计数为351 - 500个/微升，35%的计数高于500个/微升。
在这个公共部门工作人员中，每7名护士和护生中就有1人艾滋病毒呈阳性。很大一部分医护人员的CD4细胞计数低于350个/微升，根据南非治疗指南，许多人已经符合抗逆转录病毒治疗的条件。鉴于南非护士供应短缺，了解该工作人员群体中的感染率并提供有效的艾滋病治疗对于满足未来人员配备需求至关重要。
