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Mucormycosis presenting as recurrent gastric perforation in a patient with Crohn's disease on glucocorticoid, 6-mercaptopurine, and infliximab therapy.

作者信息

Devlin Shane M, Hu Bing, Ippoliti Andrew

机构信息

Cedars-Sinai Medical Center, Inflammatory Bowel Disease Center, 8730 Alden Drive, Suite E221, Los Angeles, CA 90048, USA.

出版信息

Dig Dis Sci. 2007 Sep;52(9):2078-81. doi: 10.1007/s10620-006-9455-z. Epub 2007 Apr 4.

DOI:10.1007/s10620-006-9455-z
PMID:17406841
Abstract
摘要

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Mucormycosis presenting as recurrent gastric perforation in a patient with Crohn's disease on glucocorticoid, 6-mercaptopurine, and infliximab therapy.毛霉菌病在一名接受糖皮质激素、6-巯基嘌呤和英夫利昔单抗治疗的克罗恩病患者中表现为复发性胃穿孔。
Dig Dis Sci. 2007 Sep;52(9):2078-81. doi: 10.1007/s10620-006-9455-z. Epub 2007 Apr 4.
2
Avoidance of steroids by the early use of infliximab and 6-mercaptopurine in an adolescent with active Crohn's colitis.在一名患有活动性克罗恩病结肠炎的青少年中,通过早期使用英夫利昔单抗和6-巯基嘌呤避免使用类固醇。
Am J Gastroenterol. 2001 Dec;96(12):3444-5. doi: 10.1111/j.1572-0241.2001.05380.x.
3
Combining infliximab with 6-mercaptopurine/azathioprine for fistula therapy in Crohn's disease.英夫利昔单抗联合6-巯基嘌呤/硫唑嘌呤用于克罗恩病瘘管治疗
Am J Gastroenterol. 2002 Aug;97(8):2022-5. doi: 10.1111/j.1572-0241.2002.05918.x.
4
Infliximab and azathioprine: bridge or parachute?英夫利昔单抗和硫唑嘌呤:桥梁还是降落伞?
Gastroenterology. 2006 Apr;130(4):1354-7. doi: 10.1053/j.gastro.2006.02.038.
5
Fatal disseminated cytomegalovirus infection associated with infliximab and 6-mercaptopurine therapy in a child with Crohn disease.一名克罗恩病患儿在接受英夫利昔单抗和6-巯基嘌呤治疗后发生致命性播散性巨细胞病毒感染。
Pediatr Infect Dis J. 2009 Jun;28(6):556. doi: 10.1097/INF.0b013e3181a39571.
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[Chronically active Crohn's disease].[慢性活动性克罗恩病]
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Dis Colon Rectum. 2011 Jan;54(1):15-20. doi: 10.1007/DCR.0b013e3181fc9f04.
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Case records of the Massachusetts General Hospital. Case 8-2006. A 71-year-old woman with Crohn's disease and altered mental status.马萨诸塞州总医院病例记录。病例8 - 2006。一名71岁患有克罗恩病且精神状态改变的女性。
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Steroid-independent Crohn's disease patients also benefit from combination therapy of infliximab plus azathioprine.对类固醇无反应的克罗恩病患者也能从英夫利昔单抗加硫唑嘌呤的联合治疗中获益。
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J Fungi (Basel). 2025 Apr 9;11(4):298. doi: 10.3390/jof11040298.
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Colonic Mucormycosis in Fistulizing Crohn's Disease.瘘管性克罗恩病中的结肠毛霉菌病
J Emerg Trauma Shock. 2024 Apr-Jun;17(2):107-110. doi: 10.4103/jets.jets_69_23. Epub 2023 Dec 4.
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Behçet's Disease with Bilateral Renal Infarction Due to Mucormycosis.贝赫切特病伴双侧肾梗死,由毛霉菌引起。

本文引用的文献

1
Novel perspectives on mucormycosis: pathophysiology, presentation, and management.毛霉菌病的新视角:病理生理学、临床表现及治疗
Clin Microbiol Rev. 2005 Jul;18(3):556-69. doi: 10.1128/CMR.18.3.556-569.2005.
2
A rare cause of intestinal perforation in an extreme low birth weight infant--gastrointestinal mucormycosis: a case report.极低出生体重儿肠道穿孔的罕见原因——胃肠道毛霉菌病:一例报告
J Perinatol. 2004 May;24(5):319-21. doi: 10.1038/sj.jp.7211090.
3
Outbreak of gastric mucormycosis associated with the use of wooden tongue depressors in critically ill patients.
Intern Med. 2022 Apr 1;61(7):1077-1083. doi: 10.2169/internalmedicine.7462-21. Epub 2021 Sep 18.
4
COVID-19-associated opportunistic infections: a snapshot on the current reports.COVID-19 相关机会性感染:当前报告简述。
Clin Exp Med. 2022 Aug;22(3):327-346. doi: 10.1007/s10238-021-00751-7. Epub 2021 Aug 23.
5
A Rare Cause of Massive Upper Gastrointestinal Hemorrhage in Immunocompromised Host.免疫功能低下宿主发生大量上消化道出血的罕见原因。
Gastroenterology Res. 2012 Feb;5(1):33-36. doi: 10.4021/gr400w. Epub 2012 Jan 20.
6
Epidemiology and Clinical Characteristics of Mucormycosis in Patients with Leukemia; A 21-year Experience from Southern Iran.白血病患者毛霉菌病的流行病学及临床特征:来自伊朗南部的21年经验
Bull Emerg Trauma. 2014 Jan;2(1):38-43.
7
Successful Treatment of Primary Cutaneous Mucormycosis Complicating Anti-TNF Therapy with a Combination of Surgical Debridement and Oral Posaconazole.手术清创术联合口服泊沙康唑成功治疗抗TNF治疗并发的原发性皮肤毛霉菌病
Mycopathologia. 2015 Oct;180(3-4):187-92. doi: 10.1007/s11046-015-9914-1. Epub 2015 Jun 26.
8
Mucormycosis in patients with inflammatory bowel disease: case series and review of the literature.炎症性肠病患者的毛霉菌病:病例系列及文献综述
Case Rep Med. 2014;2014:637492. doi: 10.1155/2014/637492. Epub 2014 Apr 27.
9
Coinfection of pulmonary mucormycosis and aspergillosis presenting as bilateral vocal cord palsy.肺部毛霉菌病和曲霉菌病合并感染表现为双侧声带麻痹。
BMJ Case Rep. 2013 Aug 20;2013:bcr2013009615. doi: 10.1136/bcr-2013-009615.
10
Pulmonary mucormycosis: an emerging infection.肺毛霉病:一种新出现的感染性疾病。
Case Rep Pulmonol. 2012;2012:120809. doi: 10.1155/2012/120809. Epub 2012 Dec 12.
危重症患者中与使用木质压舌板相关的胃毛霉病暴发。
Intensive Care Med. 2004 Apr;30(4):724-8. doi: 10.1007/s00134-003-2132-1. Epub 2004 Feb 26.
4
Breakthrough zygomycosis after voriconazole treatment in recipients of hematopoietic stem-cell transplants.造血干细胞移植受者伏立康唑治疗后发生的突破性接合菌病。
N Engl J Med. 2004 Feb 26;350(9):950-2. doi: 10.1056/NEJM200402263500923.
5
Abdominal wall mucormycosis successfully treated with amphotericin and itraconazole.两性霉素和伊曲康唑成功治疗腹壁毛霉病。
J Infect. 2002 Apr;44(3):203-4. doi: 10.1053/jinf.2002.0972.
6
[Risk factor for invasive zygomycosis in patients with hematologic malignancies].[血液系统恶性肿瘤患者侵袭性毛霉病的危险因素]
Mycoses. 2002;45 Suppl 1:27-30. doi: 10.1111/j.1439-0507.2002.tb04542.x.
7
Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients.造血干细胞移植受者霉菌感染的流行病学及转归
Clin Infect Dis. 2002 Apr 1;34(7):909-17. doi: 10.1086/339202. Epub 2002 Feb 26.
8
Disseminated mucormycosis due to Absidia corymbifera in a patient with inflammatory bowel disease.一名炎症性肠病患者发生由伞枝犁头霉引起的播散性毛霉病。
Clin Microbiol Infect. 1997 Apr;3(2):268-270. doi: 10.1111/j.1469-0691.1997.tb00611.x.
9
Hepatic and small bowel mucormycosis after chemotherapy in a patient with acute lymphocytic leukemia.一名急性淋巴细胞白血病患者化疗后发生肝和小肠毛霉菌病。
J Korean Med Sci. 2000 Jun;15(3):351-4. doi: 10.3346/jkms.2000.15.3.351.
10
Zygomycosis in the 1990s in a tertiary-care cancer center.20世纪90年代一家三级护理癌症中心的接合菌病。
Clin Infect Dis. 2000 Jun;30(6):851-6. doi: 10.1086/313803. Epub 2000 Jun 13.