Suppr超能文献

肺部毛霉菌病和曲霉菌病合并感染表现为双侧声带麻痹。

Coinfection of pulmonary mucormycosis and aspergillosis presenting as bilateral vocal cord palsy.

作者信息

Mahadevaiah Arun H, Rajagopalan Natarajan, Patil Mahantesh, C Shivaprasad

机构信息

Department of Pulmonology and Critical Care, Narayana Hrudayalaya Hospital, Bangalore, Karnataka, India.

出版信息

BMJ Case Rep. 2013 Aug 20;2013:bcr2013009615. doi: 10.1136/bcr-2013-009615.

Abstract

Invasive pulmonary coinfection with Mucor and Aspergillus is rare. Bilateral vocal cord paralysis resulting from coinfection with these two fungi to our knowledge has not been reported in the literature. We report a young woman with diabetes who presented with symptoms of community acquired pneumonia in association with hoarseness of voice. Investigations revealed air space consolidation of the right upper lobe, evidence of mediastinal involvement extending into the paratracheal space and entrapment of right upper lobe pulmonary artery. Bronchoscopy revealed bilateral vocal cord paralysis and sloughing of mucosa of the right upper lobe bronchus and the bronchus intermedius. Microbiological and pathological results confirmed Mucor and Aspergillus. Extensive vascular and mediastinal involvement precludes surgical debridement. Despite aggressive medical management the patient deteriorated and died of respiratory failure. Strong suspicion of invasive fungal infections in immune compromised patients presenting with unresolving pneumonia and hoarseness of voice, early aggressive treatment is crucial for the patient survival.

摘要

毛霉和曲霉的侵袭性肺部混合感染较为罕见。据我们所知,文献中尚未报道过这两种真菌混合感染导致双侧声带麻痹的情况。我们报告了一名患有糖尿病的年轻女性,她出现了社区获得性肺炎的症状并伴有声音嘶哑。检查发现右上叶实变,有纵隔受累延伸至气管旁间隙的证据以及右上叶肺动脉受压。支气管镜检查显示双侧声带麻痹,右上叶支气管和中间支气管黏膜脱落。微生物学和病理学结果证实为毛霉和曲霉。广泛的血管和纵隔受累使手术清创无法进行。尽管进行了积极的药物治疗,患者病情仍恶化并死于呼吸衰竭。对于出现持续性肺炎和声音嘶哑的免疫功能低下患者,高度怀疑侵袭性真菌感染时,早期积极治疗对患者生存至关重要。

相似文献

4
Pulmonary and Co-Infection: A report of two cases.肺部合并感染:两例报告。
Sultan Qaboos Univ Med J. 2021 Aug;21(3):495-498. doi: 10.18295/squmj.8.2021.126. Epub 2021 Aug 29.
5
Left vocal cord paralysis as a primary manifestation of invasive pulmonary aspergillosis in a nonimmunocompromised host.
Arch Otolaryngol Head Neck Surg. 1999 Jun;125(6):691-3. doi: 10.1001/archotol.125.6.691.

引用本文的文献

7
Pulmonary and Co-Infection: A report of two cases.肺部合并感染:两例报告。
Sultan Qaboos Univ Med J. 2021 Aug;21(3):495-498. doi: 10.18295/squmj.8.2021.126. Epub 2021 Aug 29.

本文引用的文献

1
Pulmonary mucormycosis: an emerging infection.肺毛霉病:一种新出现的感染性疾病。
Case Rep Pulmonol. 2012;2012:120809. doi: 10.1155/2012/120809. Epub 2012 Dec 12.
2
Zygomycosis in Immunocompromised non-Haematological Patients.免疫功能低下的非血液系统患者中的接合菌病。
Mediterr J Hematol Infect Dis. 2011;3(1):e2011012. doi: 10.4084/MJHID.2011.012. Epub 2011 Mar 15.
3
[Tracheal mucormycosis].[气管毛霉病]
Arch Bronconeumol. 2009 May;45(5):260-1. doi: 10.1016/j.arbres.2009.01.010. Epub 2009 Apr 29.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验