Wu Xiaocheng, Chen Vivien W, Andrews Patricia A, Ruiz Bernardo, Correa Pelayo
Epidemiology, Louisiana State University Health Sciences Center, School of Public Health, 2021 Lakeshore Dr. Suite 210, New Orleans, LA 70122, USA.
Cancer Causes Control. 2007 Aug;18(6):585-93. doi: 10.1007/s10552-007-9000-1. Epub 2007 Apr 4.
We examined subsite- and histology-specific esophageal and gastric cancer incidence patterns among Hispanics/Latinos and compared them with non-Hispanic whites and non-Hispanic blacks.
Data on newly diagnosed esophageal and gastric cancers for 1998-2002 were obtained from 37 population-based central cancer registries, representing 66% of the Hispanic population in the United States. Age-adjusted incidence rates (2000 US) were computed by race/ethnicity, sex, anatomic subsite, and histology. The differences in incidence rates between Hispanics and non-Hispanics were examined using the two-tailed z-statistic.
Squamous cell carcinoma accounted for 50% and 57% of esophageal cancers among Hispanic men and women, respectively, while adenocarcinoma accounted for 43% among Hispanic men and 35% among Hispanic women. The incidence rate of squamous cell carcinoma was 48% higher among Hispanic men (2.94 per 100,000) than non-Hispanic white men (1.99 per 100,000) but about 70% lower among Hispanics than non-Hispanic blacks, for both men and women. In contrast, the incidence rates of esophageal adenocarcinoma were lower among Hispanics than non-Hispanic whites (58% lower for men and 33% for women) but higher than non-Hispanic blacks (70% higher for men and 64% for women). Cardia adenocarcinoma accounted for 10-15% of gastric cancers among Hispanics, and the incidence rate among Hispanic men (2.42 per 100,000) was 33% lower than the rate of non-Hispanic white men (3.62 per 100,000) but 37% higher than that of non-Hispanic black men. The rate among Hispanic women (0.86 per 100,000), however, was 20% higher than that of non-Hispanic white women (0.72 per 100,000) and 51% higher than for non-Hispanic black women. Gastric non-cardia cancer accounted for approximately 50% of gastric cancers among Hispanics (8.32 per 100,000 for men and 4.90 per 100,000 for women), and the rates were almost two times higher than for non-Hispanic whites (2.95 per 100,000 for men and 1.72 per 100,000 for women) but about the same as the non-Hispanic blacks.
Subsite- and histology-specific incidence rates of esophageal and gastric cancers among Hispanics/Latinos differ from non-Hispanics. The incidence rates of gastric non-cardia cancer are almost two times higher among Hispanics than non-Hispanic whites, both men and women. The rates of gastric cardia cancer are lower among Hispanics than non-Hispanic whites for men but higher for women. The rates of esophageal and gastric cardia adenocarcinomas are higher among Hispanics than non-Hispanic blacks.
我们研究了西班牙裔/拉丁裔人群中特定亚部位和组织学类型的食管癌和胃癌发病率模式，并将其与非西班牙裔白人及非西班牙裔黑人进行比较。
1998 - 2002年新诊断食管癌和胃癌的数据来自37个基于人群的中央癌症登记处，这些登记处覆盖了美国66%的西班牙裔人口。按种族/族裔、性别、解剖亚部位和组织学计算年龄调整发病率（2000年美国标准）。使用双侧z统计量检验西班牙裔和非西班牙裔之间发病率的差异。
鳞状细胞癌分别占西班牙裔男性和女性食管癌的50%和57%，而腺癌在西班牙裔男性中占43%，在西班牙裔女性中占35%。西班牙裔男性鳞状细胞癌发病率（每10万人中2.94例）比非西班牙裔白人男性（每10万人中1.99例）高48%，但在西班牙裔男性和女性中，该发病率比非西班牙裔黑人低约70%。相比之下，西班牙裔食管癌腺癌发病率低于非西班牙裔白人（男性低58%，女性低33%），但高于非西班牙裔黑人（男性高70%，女性高64%）。贲门腺癌占西班牙裔胃癌的10% - 15%，西班牙裔男性发病率（每10万人中2.42例）比非西班牙裔白人男性（每10万人中3.62例）低33%，但比非西班牙裔黑人男性高37%。然而，西班牙裔女性发病率（每10万人中0.86例）比非西班牙裔白人女性（每10万人中0.72例）高20%，比非西班牙裔黑人女性高51%。胃非贲门癌约占西班牙裔胃癌的50%（男性每10万人中8.32例，女性每10万人中4.90例），其发病率几乎是非西班牙裔白人的两倍（男性每10万人中2.95例，女性每10万人中1.72例），但与非西班牙裔黑人相近。
西班牙裔/拉丁裔人群中食管癌和胃癌特定亚部位和组织学类型的发病率与非西班牙裔不同。西班牙裔胃非贲门癌发病率在男性和女性中几乎是非西班牙裔白人的两倍。西班牙裔男性贲门癌发病率低于非西班牙裔白人，女性则高于非西班牙裔白人。西班牙裔食管癌和胃贲门腺癌发病率高于非西班牙裔黑人。
