Hulcoop David G, Lautens Mark
Davenport Laboratories, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, Canada M5S 3H6.
Org Lett. 2007 Apr 26;9(9):1761-4. doi: 10.1021/ol070475w. Epub 2007 Apr 4.
[reaction: see text] An annulation reaction proceeding by the intermolecular addition of an arylpalladium(II) halide across a strained alkene, followed by an intramolecular C-H functionalization of a pendant heterocycle is described. A variety of polycyclic heterocycles have been prepared from readily accessible haloaryl heterocycles by annulation with a range of strained alkene partners.
[反应：见正文] 描述了一种环化反应，该反应通过芳基钯（II）卤化物分子间加成到一个张力烯烃上，随后进行一个侧链杂环的分子内C-H官能化。通过与一系列张力烯烃反应伙伴进行环化，已从易于获得的卤代芳基杂环制备了多种多环杂环化合物。
