Zwart Pieter, Vellema-Goud Marije G A, Brand Paul L P
Princess Amalia Children's Clinic, Isala klinieken, 8000 GK Zwolle, The Netherlands.
Acta Paediatr. 2007 Mar;96(3):401-5. doi: 10.1111/j.1651-2227.2007.00090.x.
To describe clinical characteristics of infants with colic admitted to hospital because of ongoing excessive crying (colic).
Characteristics of 104 infants admitted to hospital because of severe excessive crying (cases) were compared to those of 100 healthy thriving controls randomly selected from records of well baby clinics.
Half of the cases were reported to cry excessively from the day of birth, and feeding changes had been recommended in 77%. A medical cause of excessive crying was identified in none of the cases. Almost all infants showed a rapid transition to normal crying behaviour during admission; none cried for >3 h per day. Mean gestational age and mean Apgar scores were slightly lower in cases than in controls. There was a trend of positive family history of atopy being more common in controls (45%) than in cases (38%, p = 0.14). Feeding problems were more common in cases (71%) than in controls (36%, 95% CI for difference 21.6%-46.9%). Pregnancy or birth complications were much more common in cases (85%) than in controls (37%; 95% CI 35%-58%).
Infants with severe excessive crying show normalization of crying behaviour during hospital admission, and are unlikely to have medical causes for their colic. The most important risk factor for excessive crying was a complicated pregnancy or birth, suggesting that this might predispose parents to regard normal crying behaviour as excessive.
描述因持续性过度哭闹（腹绞痛）入院的婴儿的临床特征。
将104例因严重过度哭闹入院的婴儿（病例组）的特征与从健康婴儿诊所记录中随机选取的100例健康成长的对照组婴儿的特征进行比较。
据报告，半数病例自出生之日起就过度哭闹，77%的病例曾被建议改变喂养方式。所有病例均未发现过度哭闹的医学原因。几乎所有婴儿在住院期间哭闹行为迅速转变为正常；无人每天哭闹超过3小时。病例组的平均胎龄和平均阿氏评分略低于对照组。对照组（45%）有特应性家族史的趋势比病例组（38%，p = 0.14）更常见。病例组（71%）的喂养问题比对照组（36%，差异的95%置信区间为21.6%-46.9%）更常见。病例组（85%）的妊娠或分娩并发症比对照组（37%；95%置信区间35%-58%）更常见。
严重过度哭闹的婴儿在住院期间哭闹行为恢复正常，其腹绞痛不太可能有医学原因。过度哭闹最重要的危险因素是妊娠或分娩复杂，这表明这可能使父母倾向于将正常哭闹行为视为过度哭闹。
