Cremona Alberto R, Borga Santiago J Ramirez, Losinno Juan F, Cartasegna Luis R, Escudero Eduardo M, Fernandez Jose L, Cremona Gustavo E, Blanco Miriam E
Servicio de Infectología, Hospital Italiano de La Plata, Buenos Aires, Argentina.
Medicina (B Aires). 2007;67(1):39-43.
The embolic event (EE) increases the morbidity and mortality of infective endocarditis (IE). Prevalence of EE ranges between 22% and 50%, death rates being up to 25% of patients. EE may occur prior to diagnosis, during treatment or afterwards. The objective of this study was to evaluate the demographic, clinical, microbiological, echocardiographic and therapeutic characteristics in patients suffering from IE (with or without emboli) in order to determine predictors for EE. A descriptive study based on observations of patient population diagnosed with IE was conducted at the Hospital Italiano of La Plata during the period March 1996 - December 2004. Fifty-three patients with IE were analyzed (35 without EE and 18 with EE) in retrospect. We found that the presence of vegetations in the transthoracic (TTE) and/or transesophagic (TEE) echocardiographies at the time of diagnosis, the size > or = 10 mm and the compromise of the native mitral valve were the variables that showed significant statistical association with EE to be considered as predictors. The size _ 10 mm was the only variable associated with EE in the logistic regression analysis. During the elective antibiotic treatment, there was a reduction in EE, without their being present from the second week onwards.
栓塞事件（EE）会增加感染性心内膜炎（IE）的发病率和死亡率。EE的发生率在22%至50%之间，死亡率高达患者总数的25%。EE可能在诊断前、治疗期间或之后发生。本研究的目的是评估IE患者（有或无栓塞）的人口统计学、临床、微生物学、超声心动图和治疗特征，以确定EE的预测因素。1996年3月至2004年12月期间，在拉普拉塔意大利医院对诊断为IE的患者群体进行了一项基于观察的描述性研究。回顾性分析了53例IE患者（35例无EE，18例有EE）。我们发现，诊断时经胸（TTE）和/或经食管（TEE）超声心动图中赘生物的存在、大小≥10mm以及自身二尖瓣受累是与EE有显著统计学关联的变量，可被视为预测因素。在逻辑回归分析中，大小≥10mm是与EE相关的唯一变量。在选择性抗生素治疗期间，EE有所减少，从第二周起不再出现。
