González-Alujas M T, García del Castillo H, Evangelista A, Soler-Soler J
Servicio de Cardiología, Hospital General Universitario Vall d'Hebron, Barcelona.
Rev Esp Cardiol. 1994 Oct;47(10):672-7.
Transthoracic echocardiography is a technique with high specificity but low sensitivity in the diagnosis of valvular vegetations and infectious endocarditis complications. Recent reports have shown the transesophageal technique to be more sensitive. The aim of this study was to assess the comparative diagnostic roles of transthoracic and transesophageal echocardiography in infectious endocarditis.
Eighty-eight patients with infectious endocarditis (native valve in 71 and prosthesis in 17) were studied. All underwent transthoracic echocardiogram followed by transesophageal study to detect vegetations and possible complications, particularly paravalvular abscesses.
Transthoracic echocardiogram diagnosed vegetations in 33 (46%) of the 71 native valve endocarditis, whereas these were detected by transesophageal study in 67 (94%). In 23 patients vegetations were surgically confirmed. Transthoracic echocardiography failed to diagnose vegetations in any of the prosthetic endocarditis, whereas they were detected by transesophageal study in 11 of the 17 cases (65%). Of the 9 patients who underwent surgery in the acute phase, 5 presented vegetations on transesophageal study which were confirmed at surgery. Transesophageal echocardiography diagnosed 14 abscesses: 11 aortic peri-annular and 3 in the interfibrous. Echocardiography only detected 1 of the peri-annular aortic abscesses. All patients with peri-annular abscess underwent surgery. Transesophageal echocardiography was also more effective than transthoracic in the diagnosis of other complications: 15 vs 4 chordae tendineae mitral valve rupture and 18 vs 13 aortic valve disruption.
Transesophageal echocardiography is more effective than transthoracic echocardiography in the diagnosis of infectious endocarditis and its complications and would therefore be indicated in all cases of absence of vegetations on transthoracic echocardiography and clinical suspicion of endocarditis. Transesophageal echocardiography could be indicated in all cases of clinically suspected aortic endocarditis to rule out peri-annular abscesses.
经胸超声心动图在诊断瓣膜赘生物和感染性心内膜炎并发症方面是一种特异性高但敏感性低的技术。近期报告显示经食管技术更为敏感。本研究的目的是评估经胸和经食管超声心动图在感染性心内膜炎中的比较诊断作用。
对88例感染性心内膜炎患者(71例为天然瓣膜,17例为人工瓣膜)进行研究。所有患者均先接受经胸超声心动图检查,随后进行经食管检查,以检测赘生物和可能的并发症,特别是瓣周脓肿。
经胸超声心动图在71例天然瓣膜心内膜炎中诊断出33例(46%)有赘生物,而经食管检查发现67例(94%)有赘生物。23例患者的赘生物经手术证实。经胸超声心动图未能诊断出任何人工瓣膜心内膜炎的赘生物,而经食管检查在17例中的11例(65%)检测到赘生物。在急性期接受手术的9例患者中,5例经食管检查发现有赘生物,手术中得到证实。经食管超声心动图诊断出14个脓肿:11个主动脉瓣环周围脓肿和3个纤维间脓肿。超声心动图仅检测到1个主动脉瓣环周围脓肿。所有瓣周脓肿患者均接受了手术。经食管超声心动图在诊断其他并发症方面也比经胸超声心动图更有效:二尖瓣腱索破裂分别为15例和4例,主动脉瓣破坏分别为18例和13例。
经食管超声心动图在诊断感染性心内膜炎及其并发症方面比经胸超声心动图更有效,因此在经胸超声心动图未发现赘生物但临床怀疑心内膜炎的所有病例中均应进行经食管超声心动图检查。在临床上怀疑主动脉心内膜炎的所有病例中,均应进行经食管超声心动图检查以排除瓣周脓肿。