N-和S-α-L-阿拉伯吡喃糖基[1,2,4]三唑并[3,4-b][1,3,4]噻二唑。首次合成及生物学评价。
N- and S-alpha-l-arabinopyranosyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles. First synthesis and biological evaluation.
作者信息
Khalil Nasser S A M
机构信息
Regional Center for Food and Feed (RCFF), Agricultural Research Center, 9El Gamaa Street, Giza, Egypt.
出版信息
Eur J Med Chem. 2007 Sep;42(9):1193-9. doi: 10.1016/j.ejmech.2007.01.025. Epub 2007 Feb 21.
PMID:17408811
Abstract
First synthesis of N- and S-alpha-l-arabinopyranosyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles is described. Antimicrobial screening of two selected regioisomeric compounds against Aspergillus fumigatus, Penicillium italicum, Syncephalastrum racemosum, Candida albicans, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis and Escherichia coli are compared.
摘要
描述了 N-和 S-α-L-阿拉伯吡喃糖基[1,2,4]三唑并[3,4-b][1,3,4]噻二唑的首次合成。比较了两种选定的区域异构体化合物对烟曲霉、意大利青霉、总状共头霉、白色念珠菌、金黄色葡萄球菌、铜绿假单胞菌、枯草芽孢杆菌和大肠杆菌的抗菌筛选。
相似文献
1
N- and S-alpha-l-arabinopyranosyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles. First synthesis and biological evaluation.
Eur J Med Chem. 2007 Sep;42(9):1193-9. doi: 10.1016/j.ejmech.2007.01.025. Epub 2007 Feb 21.
2
Novel simple efficient synthetic approach toward 6-substituted-2H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole-3-thiones and first synthesis and biological evaluation of N-and S-beta-D-glucosides of the[1,2,4]triazolo [3,4-b][1,3,4]thiadiazole ring system.
Nucleosides Nucleotides Nucleic Acids. 2007;26(4):347-59. doi: 10.1080/15257770701296978.
3
Synthesis of some new 1,3/ or 1,4-bis(glucopyranosyl-1,2,4-triazol-5-ylthio)propanes/ or butanes as potential antimicrobial agents.
Nucleosides Nucleotides Nucleic Acids. 2005;24(9):1353-72. doi: 10.1080/15257770500230632.
4
Synthesis and antimicrobial evaluation of indole containing derivatives of 1,3,4-thiadiazole, 1,2,4-triazole and their open-chain counterparts.
Arzneimittelforschung. 1997 Mar;47(3):307-10.
5
First synthesis and antimicrobial activity Of N- and S-alpha-L-arabinopyranosyl-1,2,4-triazoles.
Nucleosides Nucleotides Nucleic Acids. 2007;26(4):361-77. doi: 10.1080/15257770701296986.
6
A facile synthesis, structure, and antimicrobial evaluation of novel 4-arylhydrazono-5-trifluoromethyl-2,4-dihydropyrazol-3-ones, their N- and N,O-bis-beta-D-glucosides.
Carbohydr Res. 2009 Sep 8;344(13):1654-9. doi: 10.1016/j.carres.2009.06.003. Epub 2009 Jun 6.
7
Synthesis of some 1.3.4-thiadiazoles of possible antimicrobial activity.
Pharmazie. 1984 Feb;39(2):101-3.
8
Synthesis and antimicrobial activity of some 2,5-disubstituted 1,3,4,-thiadiazole derivatives.
Farmaco. 1996 Jan;51(1):71-4.
9
Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines bearing trichlorophenyl moiety.
Eur J Med Chem. 2008 Apr;43(4):808-15. doi: 10.1016/j.ejmech.2007.06.026. Epub 2007 Jul 17.
引用本文的文献
1
One-pot synthesis of novel chiral β-amino acid derivatives by enantioselective Mannich reactions catalyzed by squaramide cinchona alkaloids.
Molecules. 2013 May 23;18(6):6142-52. doi: 10.3390/molecules18066142.
Zotero 插件