Hayat S, Al-Mutairy M, Zubaid M, Suresh C
Department of Medicine, Mubarak Al-Kabeer Hospital, Kuwait.
Med Princ Pract. 2007;16(3):234-6. doi: 10.1159/000100397.
To report the occurrence of acute myocardial infarction (MI) associated with the intake of oral sildenafil (Viagra) in a nitrate-free patient without previous history of coronary artery disease.
A 50-year-old manual laborer was admitted to the hospital with acute inferoposterior wall MI occurring approximately 30 min after taking oral sildenafil 50 mg. This occurred before any attempted sexual activity. Subsequent angiography showed a 70% stenotic lesion in the midsegment of the dominant circumflex artery. The Naranjo scale indicated that sildenafil was a probable cause of MI.
This report shows a rare sildenafil-associated MI in a nitrate-free patient without a previous history of coronary artery disease.
报告一名无冠状动脉疾病既往史且未服用硝酸盐类药物的患者在口服西地那非（万艾可）后发生急性心肌梗死（MI）的情况。
一名50岁体力劳动者在口服50毫克西地那非后约30分钟因急性下后壁心肌梗死入院，此情况发生在任何性活动尝试之前。随后的血管造影显示优势回旋支动脉中段有70%的狭窄病变。Naranjo量表表明西地那非可能是心肌梗死的病因。
本报告显示了一名无冠状动脉疾病既往史且未服用硝酸盐类药物的患者发生罕见的西地那非相关性心肌梗死。
