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墨西哥城慢性阻塞性肺疾病患者的室内、室外和个人细颗粒物浓度之间的关系以及室内-室外比率的预测因素。

Relationship between indoor, outdoor, and personal fine particle concentrations for individuals with COPD and predictors of indoor-outdoor ratio in Mexico city.

作者信息

Cortez-Lugo Marlene, Moreno-Macias Hortensia, Holguin-Molina Fernando, Chow Judith C, Watson John G, Gutiérrez-Avedoy Victor, Mandujano Francisco, Hernández-Avila Mauricio, Romieu Isabelle

机构信息

Instituto Nacional de Salud Pública, Centro de Investigaciones en Salud poblacional, Cuernavaca Mor., México.

出版信息

J Expo Sci Environ Epidemiol. 2008 Jan;18(1):109-15. doi: 10.1038/sj.jes.7500557. Epub 2007 Apr 4.

DOI:10.1038/sj.jes.7500557
PMID:17410116
Abstract

Personal exposure and indoor and outdoor exposure to PM(10) and PM(2.5) of 38 individuals with chronic obstructive pulmonary disease (COPD) was characterized from February through November 2000. All participants lived in Mexico City and were selected based on their area of residence southeast (n=15), downtown (n=15), and southwest (n=8). Participants were monitored at home using personal PM(2.5) monitoring devices. Indoor and outdoor levels of PM(10) and PM(2.5) were measured using MiniVol samplers. Concurrent individual exposure measurements, indoor and outdoor levels of PM(2.5), which averaged 38.4 (SD 21.4), 30.6 (SD 15.8), and 30.5 mug/m(3) (SD 19.4), respectively. Indoor PM(2.5) concentrations explained 40% of the variability of personal exposure. In addition, the factors that most affected personal exposure were regular indoor contact with animals, mold, cooking activities, and aerosol use, indicating that internal sources may largely affect individual exposure.

摘要

2000年2月至11月,对38名慢性阻塞性肺疾病(COPD)患者的个人暴露以及室内外PM10和PM2.5暴露情况进行了特征分析。所有参与者居住在墨西哥城,根据其居住区域分为东南部(n = 15)、市中心(n = 15)和西南部(n = 8)进行选择。使用个人PM2.5监测设备对参与者在家中进行监测。使用MiniVol采样器测量室内外PM10和PM2.5水平。同时进行的个人暴露测量显示,室内和室外PM2.5水平分别平均为38.4(标准差21.4)、30.6(标准差15.8)和30.5微克/立方米(标准差19.4)。室内PM2.5浓度解释了个人暴露变异性的40%。此外,对个人暴露影响最大的因素是经常在室内接触动物、霉菌、烹饪活动和气溶胶使用,这表明内部来源可能在很大程度上影响个人暴露。

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