Jayanthi Venkataraman, Randhir Jesudoss, Rajesh Natrayan
Department of Gastroenterology, Stanley Medical College and Hospital, Chennai, India.
J Gastrointestin Liver Dis. 2007 Mar;16(1):101-3.
Primary lymphoma of the pancreas is a rare form of extranodal lymphoma accounting for less than 0.5% of pancreatic tumors. Percutaneous fine-needle aspiration of the pancreas with histopathological examination and immunohistochemical assay confirm the diagnosis. A 73 year old male presented with recurrent pancreatic type abdominal pain with significant weight loss over 1 year. He was pale with ill defined epigastric mass. Contrast enhanced CT showed an ill defined poorly marginated non enhancing hypodense mass lesion involving the body of the pancreas. CA 19-9 was normal. CT guided aspiration cytology was suggestive of hemolymphoid malignancy. Immunohistochemistry was positive for Leukocyte Common Antigen and CD 34. It was negative for CD3 and CD 20 indicating an undifferentiated lymphoma. Patient received two sessions of chemotherapy and was followed-up.
胰腺原发性淋巴瘤是一种罕见的结外淋巴瘤形式，占胰腺肿瘤的比例不到0.5%。通过胰腺经皮细针穿刺活检及组织病理学检查和免疫组化检测可确诊。一名73岁男性，出现反复的胰腺型腹痛，并在1年多时间里体重显著减轻。他面色苍白，上腹部有边界不清的肿块。增强CT显示胰腺体部有一个边界不清、边缘模糊的非强化低密度肿块病变。CA 19-9正常。CT引导下细针穿刺细胞学检查提示为血液淋巴系统恶性肿瘤。免疫组化显示白细胞共同抗原和CD 34呈阳性。CD3和CD 20呈阴性，提示为未分化淋巴瘤。患者接受了两个疗程的化疗并进行了随访。
