Davis L J, Paragina S, Kincaid M C
Bethesda Eye Institute, St. Louis University School of Medicine, Missouri.
Optom Vis Sci. 1992 Jan;69(1):66-71. doi: 10.1097/00006324-199201000-00011.
We present three patients who were found to have unusual pigmentation of the bulbar conjunctiva. The areas, 1 to 2 mm in size, were translucent with dark black dust-like particles randomly placed within well defined borders. These specks were usually elevated, had a granular texture, and appeared to be overlying pingueculae. All three patients wore rigid gas permeable contact lenses, were found to have either a short tear break-up time or deficient tear aqueous layer, had associated 3:00 and 9:00 o'clock staining, and routinely used heavy mascara and/or eyeliner. In one patient, the areas resolved on discontinuing contact lens wear. The elevated areas may be associated with minor discomfort. We propose that a deficient tear layer and drying adjacent to the lens edge may compromise the conjunctival epithelium and prevent efficient washing of the pigment particles from the conjunctiva, allowing these granules to become embedded in the epithelium. Additional causes of conjunctival pigmentation are discussed.
我们报告了三名患者，他们被发现球结膜有异常色素沉着。这些区域大小为1至2毫米，呈半透明状，有深黑色粉尘样颗粒随机分布在界限分明的边界内。这些斑点通常隆起，质地呈颗粒状，似乎覆盖在睑裂斑上。所有三名患者均佩戴硬性透气性隐形眼镜，发现泪膜破裂时间短或泪液水液层不足，伴有3点和9点位置的染色，并且经常使用浓重的睫毛膏和/或眼线笔。在一名患者中，停止佩戴隐形眼镜后这些区域消退。隆起区域可能伴有轻微不适。我们认为，泪液层不足以及镜片边缘附近的干燥可能会损害结膜上皮，并阻止色素颗粒从结膜有效冲洗掉，从而使这些颗粒嵌入上皮中。还讨论了结膜色素沉着的其他原因。
