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台湾地区精神药物使用趋势:一项基于人群的全民健康保险研究,1997 - 2004年

Trends in the use of psychotropic drugs in Taiwan: a population-based national health insurance study, 1997-2004.

作者信息

Chien I-Chia, Bih Shin-Huey, Chou Yiing-Jenq, Lin Ching-Heng, Lee Wen-Guang, Chou Pesus

机构信息

Jianan Mental Hospital, No. 80, Lane 870, Jhongshan Road, Rende Township, Tainan County 71742, Taiwan.

出版信息

Psychiatr Serv. 2007 Apr;58(4):554-7. doi: 10.1176/ps.2007.58.4.554.

Abstract

OBJECTIVE

This study examined changes in the use of psychotropic agents in Taiwan between 1997 and 2004.

METHODS

The population-based National Health Insurance database was used to detect trends in the use of psychotropic drugs in Taiwan. A dynamic random sample of 200,432 persons was gathered and followed from 1997 to 2004. Persons in the sample who had made at least one service claim during these years for either ambulatory or inpatient care with a psychotropic drug prescription were identified.

RESULTS

The prevalence of any psychotropic drug use increased from 7.1% in 1997 to 12.0% in 2004. The changes in prevalence of use of four kinds of psychotropic drugs from 1997 to 2004 were as follows: antipsychotics, 3.4% to 3.7%, although this finding was not significant; antidepressants, 2.2% to 4.4% (p<.001); mood stabilizers, .6% to 1.3% (p<.001); and anxiolytic-hypnotic drugs, 3.0% to 7.3% (p<.001).

CONCLUSIONS

Overall, the prevalence of use of three kinds of psychotropic drugs (antidepressants, mood stabilizers, and anxiolytic-hypnotic drugs) increased greatly from 1997 to 2004.

摘要

目的

本研究调查了1997年至2004年间台湾地区精神药物使用情况的变化。

方法

基于人群的全民健康保险数据库被用于检测台湾地区精神药物使用趋势。收集了一个动态随机样本,共200,432人,从1997年至2004年进行跟踪。确定样本中在这些年里至少有一次门诊或住院护理服务申请且开具了精神药物处方的人。

结果

使用任何精神药物的患病率从1997年的7.1%上升至2004年的12.0%。1997年至2004年四类精神药物使用患病率的变化如下:抗精神病药物,从3.4%至3.7%,尽管这一结果无统计学意义;抗抑郁药物,从2.2%至4.4%(p<0.001);心境稳定剂,从0.6%至1.3%(p<0.001);以及抗焦虑催眠药物,从3.0%至7.3%(p<0.001)。

结论

总体而言,1997年至2004年间,三类精神药物(抗抑郁药物、心境稳定剂和抗焦虑催眠药物)的使用患病率大幅上升。

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