Schier Joshua G, Patel Manish M, Belson Martin G, Patel Amee, Schwartz Michael, Fitzpatrick Nicole, Drociuk Dan, Deitchman Scott, Meyer Richard, Litovitz Toby, Watson William A, Rubin Carol H, Kiefer Max
Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Ga 30341, USA.
Am J Public Health. 2007 Apr;97 Suppl 1(Suppl 1):S152-7. doi: 10.2105/AJPH.2006.099903. Epub 2007 Apr 5.
In October 2003, a package containing ricin and a note threatening to poison water supplies was discovered in a South Carolina postal facility, becoming the first potential chemical terrorism event involving ricin in the United States. We examined the comprehensive public health investigation that followed and discuss the lessons learned from it.
An investigation consisting primarily of environmental sampling for ricin contamination, performance of health assessments on affected personnel, and local, regional, and national surveillance for ricin-associated illness.
Laboratory analysis of 75 environmental sampling specimens revealed no ricin contamination. Health assessments of 36 affected employees were completed. Local surveillance initially identified 3 suspected cases, and national surveillance identified 399 outliers during the 2-week period after the incident. No confirmed cases of ricin-associated illness were identified.
A multifaceted and multidisciplinary approach is required for an effective public health response to a chemical threat such as ricin. The results of all of the described activities were used to determine that the facility was safe to reopen and that no public health threat existed.
2003年10月,在南卡罗来纳州的一个邮政设施中发现了一个装有蓖麻毒素的包裹以及一张威胁要毒害供水系统的纸条,这成为美国首例涉及蓖麻毒素的潜在化学恐怖主义事件。我们审视了随后展开的全面公共卫生调查,并讨论从中吸取的经验教训。
调查主要包括对蓖麻毒素污染进行环境采样、对受影响人员进行健康评估,以及针对蓖麻毒素相关疾病进行地方、区域和全国性监测。
对75份环境采样标本的实验室分析未发现蓖麻毒素污染。完成了对36名受影响员工的健康评估。事件发生后的两周内,地方监测最初发现了3例疑似病例,全国性监测发现了399例异常病例。未发现蓖麻毒素相关疾病的确证病例。
对于诸如蓖麻毒素这样的化学威胁,有效的公共卫生应对需要多方面、多学科的方法。上述所有活动的结果被用于确定该设施重新开放是安全的,且不存在公共卫生威胁。