茶碱、胰高血糖素和SQ - 20009在犬体内诱导产生的胆汁利胆增量的共同特征。
Characteristics common to choleretic increments of bile induced by theophylline, glucagon and SQ-20009 in the dog.
作者信息
Barnhart J L, Combes B
出版信息
Proc Soc Exp Biol Med. 1975 Dec;150(3):591-6. doi: 10.3181/00379727-150-39086.
PMID:174139
Abstract
Theophylline, glucagon, and SQ-20009 induce a choleresis in the dog characterized by a proportionate increase in erythritol clearance and bile flow, no increase in bile salt excretion, and by an isosmotic solution of similar electrolyte composition. The increment in bile appears to originate at the canaliculus in response to increased cyclic-AMP.
摘要
茶碱、胰高血糖素和SQ - 20009可引起犬胆汁分泌增加，其特征为赤藓醇清除率和胆汁流量成比例增加，胆盐排泄无增加，且胆汁为具有相似电解质组成的等渗溶液。胆汁增加似乎源于胆小管对环磷酸腺苷增加的反应。
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