Behbehani Raed, Sharfuddin Khaja, Anim J T
Department of Ophthalmology, Ibn Sina Hospital, Kuwait City, Kuwait.
J Neuroophthalmol. 2007 Mar;27(1):41-4. doi: 10.1097/WNO.0b013e31803312fa.
A 25-year-old man with chronically progressive ptosis and bilateral ophthalmoplegia displayed fatigability and fluctuation of ptosis, an abnormal single-fiber electromyogram, and a markedly elevated acetylcholine receptor antibody level. Yet a muscle biopsy showed clear evidence of a mitochondrial cytopathy, and the clinical features did not improve after treatment with prednisone. This case emphasizes the difficulty in differentiating mitochondrial cytopathy from myasthenia gravis and points out that elevated acetylcholine receptor antibody levels may occur in nonmyasthenic conditions.
一名25岁男性，患有慢性进行性上睑下垂和双侧眼肌麻痹，表现为上睑下垂的疲劳性和波动性、单纤维肌电图异常以及乙酰胆碱受体抗体水平显著升高。然而，肌肉活检显示出线粒体细胞病的明确证据，且泼尼松治疗后临床症状未改善。该病例强调了区分线粒体细胞病和重症肌无力的困难，并指出乙酰胆碱受体抗体水平升高可能出现在非重症肌无力的情况下。
