Peculiarities of active avoidance conditioning in rats with various forms of inherited arterial hypertension.
作者信息
Loskutova L V, Filatov A V, Dubrovia N I, Markel' A L
机构信息
Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences.
出版信息
Bull Exp Biol Med. 2006 Oct;142(4):406-8. doi: 10.1007/s10517-006-0377-8.
Peculiarities of active avoidance conditioning were studied in NISAG rats (hereditary stress-induced arterial hypertension) and spontaneously hypertensive SHR rats. Conditioning was successful in 90% normotensive Wistar rats and in only 9.1% NISAG rats. Hypertensive SHR rats were intermediate between Wistar and NISAG rats by their learning capacity (66.7%). Our results suggest that differences in learning capacity of hypertensive rats are determined by genetic characteristics of animal behavior and emotional state, rather than blood pressure elevation.
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