11-去氧米索前列醇（前列腺素E1类似物）的胃保护特性及其对消化性溃疡大鼠胃组织中唾液酸水平的影响。
Gastroprotective properties of 11-deoxymisoprostol (prostaglandin E1 analog) and its effect on the level of sialic acids in gastric tissue of rats with peptic ulcer.
作者信息
Baschenko N Zh, Sapozhnikova T A, Gabdrakhmanova S F, Makara N S, Khisamutdinova R Yu, Zarudii F S, Ivanova N A, Nazarov V S
机构信息
Department of Pharmacology No. 1, Bashkir State Medical University.
出版信息
Bull Exp Biol Med. 2006 Oct;142(4):467-9. doi: 10.1007/s10517-006-0394-7.
PMID:17415439
Abstract
11-Deoxymisoprostol (prostaglandin E1 analog) exhibited a pronounced gastroprotective effect on various models of experimental ulcers induced by nonsteroid antiinflammatory drugs. A relationship between high resistance of the gastroduodenal mucosa under the effect of 11-deoxymisoprostol and changes in the level of sialic acid was detected.
摘要
11-脱氧米索前列醇（前列腺素E1类似物）对非甾体抗炎药诱导的各种实验性溃疡模型均表现出显著的胃保护作用。检测到11-脱氧米索前列醇作用下胃十二指肠黏膜的高抗性与唾液酸水平变化之间的关系。
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