糖尿病性牙周病中颊黏膜的结构反应

Structural reactions of the buccal mucosa in diabetic parodontopathy.

作者信息

Balakhonov L V, Nepomnyashchikh L M, Aidagulova S V, Bakarev M A, Vlasova L F

机构信息

Laboratory of General Pathological Anatomy, Institute of Regional Pathology and Pathomorphology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk.

出版信息

Bull Exp Biol Med. 2006 Nov;142(5):633-6. doi: 10.1007/s10517-006-0436-1.

DOI:10.1007/s10517-006-0436-1

PMID:17415480

Abstract

Pronounced changes in the capillaries, hemodynamic disorders, epitheliocyte degeneration and atrophy develop in the buccal mucosa of patients with types I and II diabetes mellitus in the absence of inflammatory cellular infiltration or with facultative infiltration. The morphogenesis of pathological changes can be regarded as primary diabetic microangiopathy causing metabolic disorders with the development of degenerative and atrophic changes in all structural components of the buccal mucosa and development of diabetic parodontopathy, a primary degenerative process.

摘要

I型和II型糖尿病患者的颊黏膜会出现明显的毛细血管变化、血液动力学紊乱、上皮细胞变性和萎缩，且无炎性细胞浸润或有兼性浸润。病理变化的形态发生可被视为原发性糖尿病微血管病变，其导致代谢紊乱，进而引起颊黏膜所有结构成分的变性和萎缩变化，并引发糖尿病性牙周病，这是一个原发性退行性过程。