[体外循环在累及左心房的局部晚期肺癌治疗中的价值]
[Value of cardiopulmonary bypass for locally advanced lung cancer involving the left atrium].
作者信息
Zhao Bo, Chen Wei-hua, Sun Wei, Fu Xiang-ning, Li Jun, Pan Tie-cheng
机构信息
Department of Cardiothoracic Surgery, Tongji Hospital, Tongli Medical College, Huazhong University of Sciences and Technology, Wuhan 430030, China.
出版信息
Zhonghua Zhong Liu Za Zhi. 2006 Nov;28(11):860-2.
OBJECTIVE
To review the experience and assess the value of cardiopulmonary bypass (CPB) in the treatment of locally advanced lung cancer involving the left atrium.
METHODS
From Jan. 1999 to Dec. 2002, lobectomy or pneumonectomy combined with partial resection of the left atrium were carried out in 52 such patients, which included 13 with assistance of CPB and 39 without.
RESULTS
There was one postoperative death in each of the CPB and non-CPB groups due to brbonchopleural fistula and pulmonary infection. Six patients in CPB and 14 in non-CPB groups developed postoperative cardiac complication including arrhythmia, pneumonia and heart failure. The 1-, 3-year survival rate of CPB and non-CPB groups was 69.3%, 66.7% and 38.5%, 38.5%, respectively.
CONCLUSION
Combined resection of locally advanced lung cancer with partially involved left atrium through cardiopulmonary bypass was safe and effective, and may not increase the postoperative complication and risk.
目的
回顾体外循环（CPB）在治疗累及左心房的局部晚期肺癌中的经验并评估其价值。
方法
1999年1月至2002年12月，对52例此类患者实施了肺叶切除术或全肺切除术联合左心房部分切除术，其中13例在体外循环辅助下进行，39例未使用体外循环。
结果
体外循环组和非体外循环组各有1例患者术后因支气管胸膜瘘和肺部感染死亡。体外循环组6例患者和非体外循环组14例患者术后出现心脏并发症，包括心律失常、肺炎和心力衰竭。体外循环组和非体外循环组的1年、3年生存率分别为69.3%、66.7%和38.5%、38.5%。
结论
通过体外循环对累及左心房的局部晚期肺癌进行联合切除是安全有效的，且可能不会增加术后并发症和风险。
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