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接受择期矫形手术而禁食马匹的代谢和临床特征。

Metabolic and clinical traits in horses undergoing feed deprivation for elective orthopaedic surgery.

作者信息

Reinprecht Birgit, Hackl Sigrun, Reisinger Renate, Zickl Michaela, Spona Jürgen, Stanek Christian, Zentek Jürgen

机构信息

Department of Veterinary Public Health, Institute of Nutrition, University of Veterinary Medicine of Vienna,Vienna, Austria.

出版信息

Berl Munch Tierarztl Wochenschr. 2007 Mar-Apr;120(3-4):134-40.

Abstract

The objective of this study was to investigate some metabolic and clinical effects of feed deprivation in horses that were submitted for orthopaedic surgery. The effects of preoperative feed restriction were investigated in 20 horses submitted for elective orthopaedic surgery. The patients were fasted from 12 hours before until 4 hours after surgery. Serum free amino acids, glucose,free fatty acids (FFA), white blood cell counts, creatine kinase (CK) and aspartate aminotransferase (AST) were determined 24 hours before surgery, 2 hours after the end of anaesthesia and 24 and 72 hours after surgery. Besides, abdominal sounds, appetite, faecal quality and body temperature were examined. Serum free amino acids did not react homogenously, concentrations were partly increasing or decreasing. Plasma glucose and FFA increased after surgery and returned to their preoperative levels 72 hours after surgery. A significant rise of the segmented granulocytes occurred 24 hours after surgery, all other parameters of the leukogram did not exceed the physiological range. AST reached its highest activity 24 hours after surgery, whereas CK activities were highest at 2 hours after surgery. Abdominal sounds were significantly reduced until 24 hours after surgery, however, appetite was not depressed. Faecal quality was physiological after surgery. Mean body temperature stayed within the physiological range. In conclusion, a relatively short perioperative fasting period had significant effects on the metabolic traits in horses, however the effects on physiological functions were minor. The consequences of major surgical procedures need to be addressed in future studies.

摘要

本研究的目的是调查接受骨科手术的马匹禁食对其代谢和临床的一些影响。对20匹接受择期骨科手术的马匹术前禁食的影响进行了研究。患者从手术前12小时禁食至手术后4小时。在手术前24小时、麻醉结束后2小时以及手术后24小时和72小时测定血清游离氨基酸、葡萄糖、游离脂肪酸(FFA)、白细胞计数、肌酸激酶(CK)和天冬氨酸转氨酶(AST)。此外,还检查了肠鸣音、食欲、粪便质量和体温。血清游离氨基酸反应不一致,浓度部分升高或降低。术后血浆葡萄糖和FFA升高,并在术后72小时恢复到术前水平。术后24小时分叶粒细胞显著升高,白细胞计数的所有其他参数均未超过生理范围。AST在术后24小时达到最高活性,而CK活性在术后2小时最高。直到术后24小时肠鸣音显著减少,然而食欲并未受到抑制。术后粪便质量正常。平均体温保持在生理范围内。总之,相对较短的围手术期禁食期对马匹的代谢特征有显著影响,然而对生理功能的影响较小。未来的研究需要探讨大型外科手术的后果。

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