Zicker S C, Rogers Q R
Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis 95616-8741.
Am J Vet Res. 1994 Jul;55(7):1020-7.
Concentrations of amino acids in plasma and whole blood in response to 10 hours of food deprivation were determined in healthy 2-day-old foals (n = 8) and were compared with control values in foals of the same age (n = 8) allowed free access to suckle. In addition, response of concentrations of amino acids in plasma to 15 minutes of free-access suckling was determined at the end of the 10-hour period in both groups. Response of 13 amino acids in plasma of food-deprived foals was significantly (P < 0.05) different, compared with that in control foals. Concentrations of 3 amino acids (alanine, glycine, and phenylalanine) in plasma increased significantly (P < 0.05), whereas concentrations of 7 amino acids (asparagine, citrulline, histidine, ornithine, proline, tryptophan, and tyrosine) in plasma decreased significantly (P < 0.05) during food deprivation. Response of concentrations of 2 amino acids (glycine and histidine) in whole blood was significantly (P < 0.05) different from that in plasma of food-deprived vs control foals. Refeeding of food-deprived foals resulted in significantly (P < 0.05) different responses for concentrations of all but 2 amino acids (cystine and taurine) in plasma, compared with responses in controls. Changes in concentrations of amino acids in plasma and whole blood of foals in response to food deprivation are similar to those in foals with septicemia and in children with grade 1 or 2 kwashiorkor. The significantly different response of food-deprived foals to refeeding may be attributable to increased protein intake or altered physiologic state.
测定了8匹健康2日龄马驹在禁食10小时后血浆和全血中的氨基酸浓度，并将其与8匹同龄且可自由吮乳的对照马驹的对照值进行比较。此外，在10小时禁食期结束时，测定了两组马驹血浆中氨基酸浓度对15分钟自由吮乳的反应。与对照马驹相比，禁食马驹血浆中13种氨基酸的反应有显著差异（P<0.05）。禁食期间，血浆中3种氨基酸（丙氨酸、甘氨酸和苯丙氨酸）的浓度显著升高（P<0.05），而7种氨基酸（天冬酰胺、瓜氨酸、组氨酸、鸟氨酸、脯氨酸、色氨酸和酪氨酸）的浓度显著降低（P<0.05）。全血中2种氨基酸（甘氨酸和组氨酸）的反应与禁食马驹和对照马驹血浆中的反应有显著差异（P<0.05）。与对照组相比，禁食马驹重新进食后，除2种氨基酸（胱氨酸和牛磺酸）外，血浆中所有氨基酸浓度的反应均有显著差异（P<0.05）。马驹血浆和全血中氨基酸浓度对禁食的反应变化与败血症马驹和1级或2级夸休可尔症儿童的反应相似。禁食马驹对重新进食的显著不同反应可能归因于蛋白质摄入量增加或生理状态改变。
