Kayýkçýolu Ozcan, Ozmen Bilgin, Seymenoglu Göktuğ, Tunali Didem, Kafesçiler Sabriye Ozkaya, Güclü Feyzullah, Hekimsoy Zeliha
Ophthalmology Department, Celal Bayar University Medical Faculty, Manisa, Turkey.
Arch Med Res. 2007 May;38(4):398-402. doi: 10.1016/j.arcmed.2006.12.008.
We undertook this study to evaluate the changes in macular edema of uncontrolled type 2 diabetes mellitus patients with the regulation of hyperglycemia.
The study population was comprised of 35 type 2 diabetes mellitus patients who had poorly regulated blood glucose values. Ophthalmic examinations including baseline and 6-month macular edema index values of patients by Heidelberg Retinal Tomography (HRT) macular module were done.
Twenty four (68.6%) female patients and 11 (31.4%) male patients with a mean age of 50.7 +/- 10.3 (mean +/- SD) years and mean diabetic duration of 9.8 +/- 7.5 years participated in the study. Twenty two (62.9%) did not have diabetic retinopathy (DR), whereas 13 (37.2%) had background DR with macular edema. There was a significant correlation between duration of diabetes and HRT-II macula edema index for the right and left eyes (r = 0.40, p = 0.21 and r = 0.40, p = 0.22, respectively).
Macular edema did not change significantly by regulation of glycemic control in the study group.
我们开展这项研究以评估血糖控制不佳的2型糖尿病患者黄斑水肿随血糖调节的变化情况。
研究人群包括35例血糖控制不佳的2型糖尿病患者。通过海德堡视网膜断层扫描（HRT）黄斑模块对患者进行眼科检查，包括基线和6个月时的黄斑水肿指数值。
24例（68.6%）女性患者和11例（31.4%）男性患者参与了研究，平均年龄为50.7±10.3（平均±标准差）岁，平均糖尿病病程为9.8±7.5年。22例（62.9%）没有糖尿病视网膜病变（DR），而13例（37.2%）有伴有黄斑水肿的背景性DR。糖尿病病程与右眼和左眼的HRT-II黄斑水肿指数之间存在显著相关性（分别为r = 0.40，p = 0.21和r = 0.40，p = 0.22）。
在研究组中，通过血糖控制调节，黄斑水肿没有显著变化。
