Albert Keith J, Bradshaw John Thomas, Knaide Tanya R, Rogers Alexis L
Artel, Inc., Technical Marketing, 25 Bradley Drive, Westbrook, ME 04092, USA.
Clin Lab Med. 2007 Mar;27(1):123-38. doi: 10.1016/j.cll.2007.01.003.
Multichannel volume dispensing devices, such as automated liquid handlers, are widely used in drug discovery assays and other high-throughput screening processes. The performance of these systems is heavily based on the ability to deliver proper volumes of specific reagents. Discussed herein is the recent research on broadening existing methods for accurately assessing liquid-handler performance when dispensing complex or nonaqueous reagents. Accurate and reliable adjustment of liquid-handler protocols for varied reagent types could have far-reaching adoption in all scientific communities.
多通道体积分配装置,如自动液体处理仪,广泛应用于药物发现检测和其他高通量筛选过程。这些系统的性能很大程度上取决于输送特定试剂适当体积的能力。本文讨论了最近关于拓宽现有方法以准确评估在分配复杂或非水试剂时液体处理仪性能的研究。针对不同试剂类型准确可靠地调整液体处理仪方案可能会在所有科学界得到广泛应用。