Varshavskiĭ V A, Luarinavichius A A, Severgina E S
Arkh Patol. 1991;53(7):19-23.
15 kidney biopsies from 13 patients with a combination of membranous nephropathy and amyloidosis were studied. Membranous nephropathy is shown to precede the development of amyloidosis which possesses all the properties of the acquired one (AA-amyloid). Transformation of membranous nephropathy into amyloidosis is due to the deficiency of the immune system characteristic of both processes. This combination is not considered as a special type of amyloidosis but as a peculiar feature of membranous nephropathy.
对13例患有膜性肾病合并淀粉样变性的患者的15份肾活检标本进行了研究。结果显示,膜性肾病先于淀粉样变性出现,后者具有所有获得性(AA型淀粉样蛋白)淀粉样变性的特征。膜性肾病转变为淀粉样变性是由于这两种疾病所共有的免疫系统缺陷所致。这种组合并不被视为一种特殊类型的淀粉样变性,而是膜性肾病的一种特殊特征。