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线粒体功能障碍:对运动表现和细胞衰老的影响。

Mitochondrial dysfunction: impact on exercise performance and cellular aging.

作者信息

Conley Kevin E, Jubrias Sharon A, Amara Catherine E, Marcinek David J

机构信息

Department of Radiology, University of Washington Medical Center, Seattle, WA 98195-7115, USA.

出版信息

Exerc Sport Sci Rev. 2007 Apr;35(2):43-9. doi: 10.1249/JES.0b013e31803e88e9.

DOI:10.1249/JES.0b013e31803e88e9
PMID:17417049
Abstract

Innovative noninvasive methods open a new window on the cell in vivo. This window reveals that the tempo of mitochondrial dysfunction with age varies among muscles and in proportion to Type II muscle fiber content. Exercise training can reverse age-related dysfunction, thereby providing an intervention to slow the pace of aging and disability in the elderly.

摘要

创新的非侵入性方法为体内细胞打开了一扇新窗口。这扇窗口揭示了线粒体功能障碍随年龄增长的节奏在不同肌肉之间存在差异,且与II型肌纤维含量成比例。运动训练可以逆转与年龄相关的功能障碍,从而为减缓老年人衰老和残疾的速度提供一种干预措施。

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