Jespersen H M, MacGregor E A, Sierks M R, Svensson B
Department of Chemistry, Carlsberg Laboratory, Copenhagen Valby, Denmark.
Biochem J. 1991 Nov 15;280 ( Pt 1)(Pt 1):51-5. doi: 10.1042/bj2800051.
Structure-prediction and hydrophobic-cluster analysis of several starch hydrolases and related enzymes indicated the organization of eleven domain types. Most enzymes possess a catalytic (beta/alpha)8-barrel and a smaller C-terminal domain as seen in crystal structures of alpha-amylase and cyclodextrin glucanotransferase. Some also have a starch-granule-binding domain. Enzymes breaking or forming endo-alpha-1,6 linkages contain domains N-terminal to the (beta/alpha)8-barrel.
几种淀粉水解酶及相关酶的结构预测和疏水簇分析表明存在11种结构域类型。如在α-淀粉酶和环糊精葡糖基转移酶的晶体结构中所见，大多数酶具有一个催化性（β/α）8桶和一个较小的C端结构域。一些酶还具有一个淀粉颗粒结合结构域。断裂或形成α-1,6-内连接的酶在（β/α）8桶的N端含有结构域。
