Grewal Satkiran S, Hunt John P, O'Connor Stephen C, Gianturco Laurie E, Richardson Matthew W, Lehmann Leslie E
Department of Pediatrics, Baystate Medical Center, Springfield, Massachusetts, USA.
Pediatr Blood Cancer. 2008 Apr;50(4):888-90. doi: 10.1002/pbc.21201.
Chronic Helicobacter pylori (H. pylori) infection has been linked to lymphoma of gastric mucosa-associated lymphoid tissue (MALT), a tumor that is typically localized at presentation. Sporadic Burkitt lymphoma (BL) frequently presents as an abdominal mass. However, primary gastric BL is unusual and the role of H. pylori in its pathogenesis is unclear. We describe a 12 year old with localized gastric BL and concurrent H. pylori infection. In this report, we discuss the potential association between H. pylori and gastric BL and also highlight certain similarities between gastric MALT lymphomas and BL arising in the stomach.
慢性幽门螺杆菌（H. pylori）感染与胃黏膜相关淋巴组织（MALT）淋巴瘤有关，这种肿瘤在发病时通常局限于局部。散发性伯基特淋巴瘤（BL）常表现为腹部肿块。然而，原发性胃BL并不常见，H. pylori在其发病机制中的作用尚不清楚。我们描述了一名患有局限性胃BL并同时感染H. pylori的12岁儿童。在本报告中，我们讨论了H. pylori与胃BL之间的潜在关联，并强调了胃MALT淋巴瘤与胃内发生的BL之间的某些相似之处。
