Veille J C, Ben-Ami M, Sivakoff M
Department of Reproductive Biology, Case Western Reserve University, Cleveland, Ohio.
Am J Perinatol. 1991 Jul;8(4):269-72. doi: 10.1055/s-2007-999394.
Range-gated pulsed Doppler has permitted the study of umbilical artery flow velocity waveforms (FVWs) in human fetuses and is becoming part of the antepartum fetal evaluation. No uniform method of describing such velocity waveforms and no significant body of normal values using pulsed Doppler can be found in the literature. The present study reports on a cohort of 268 patients who had pulsed Doppler umbilical artery FVWs performed during their pregnancy. The gestational age at the time of the study ranged between 16th and 42nd weeks of gestation in normal pregnancies. The systolic to diastolic (S/D) ratio was found progressively to decrease as gestation advanced; however, the range of normal values in this study was found to be quite large at all gestational ages. The present data represent normative data of the umbilical artery FVWs S/D ratio in a large number of normal pregnancies as shown by the follow-up of all the patients to delivery. Before umbilical artery waveform becomes part of the antenatal armamentarium, we advise caution before adopting rigid values that are derived from small groups. Lack of standard values for the 95th percentile may result in a premature delivery of an otherwise normal fetus.
距离选通脉冲多普勒技术已能够对人类胎儿的脐动脉血流速度波形（FVW）进行研究，并且正成为产前胎儿评估的一部分。在文献中找不到描述此类速度波形的统一方法，也没有大量使用脉冲多普勒的正常值。本研究报告了一组268例在孕期进行了脉冲多普勒脐动脉FVW检测的患者。在正常妊娠中，研究时的孕周在妊娠第16至42周之间。发现随着孕周增加，收缩期与舒张期（S/D）比值逐渐降低；然而，本研究中所有孕周的正常值范围都相当大。如对所有患者随访至分娩所示，目前的数据代表了大量正常妊娠中脐动脉FVW的S/D比值的标准数据。在脐动脉波形成为产前检查手段的一部分之前，我们建议在采用从小样本得出的严格数值时要谨慎。第95百分位数缺乏标准值可能会导致原本正常的胎儿早产。
