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[口腔黏膜疣状癌]

[Verrucous carcinoma of the oral mucosa].

作者信息

Rink B

机构信息

Klinik für Kiefer- und Gesichtschirurgie, der Humboldt-Universität zu Berlin.

出版信息

Laryngorhinootologie. 1991 Oct;70(10):542-5. doi: 10.1055/s-2007-998093.

Abstract

Verrucous carcinoma is a distinct variant of differentiated squamous cell carcinoma with low-grade malignancy, slow growth and no metastatic potential. Although it has been reported at extraoral sites, the tumor is mostly found in the oral mucosa. Clinically warty tumours with a grey-white, deeply cleaved surface are detected. The special feature of this tumour type is that it appears macroscopically malignant but histologically benign. The diagnosis of verrucous carcinoma may be difficult, since it is often lumped with verrucous hyperplasia or epidermoid carcinoma. In our study the clinical and histological characteristics of 32 cases of verrucous carcinoma of the oral cavity were investigated. The most common site was the mandibular buccal sulcus. The average age amount to 69 years. Adequate surgical excision is considered the treatment of choice. Because of the lack of metastatic spread a systematic treatment of the regional lymph nodes ist not mandatory. The prognosis of verrucous carcinoma is fairly good.

摘要

疣状癌是一种分化型鳞状细胞癌的独特变体,恶性程度低,生长缓慢且无转移潜能。尽管已有口外部位的报道,但该肿瘤大多见于口腔黏膜。临床上可检测到表面灰白色、有深深裂隙的疣状肿物。这种肿瘤类型的特殊之处在于,它在宏观上看似恶性,但组织学上却是良性的。疣状癌的诊断可能较为困难,因为它常与疣状增生或表皮样癌混淆。在我们的研究中,对32例口腔疣状癌的临床和组织学特征进行了调查。最常见的部位是下颌颊沟。平均年龄为69岁。充分的手术切除被认为是首选治疗方法。由于不存在转移扩散,对区域淋巴结进行系统性治疗并非必需。疣状癌的预后相当良好。

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