Theegarten D, Barfuss A, Gellrich N C, Philippou S
Abteilung für Pathologie, Ruhr-Universität, Bochum.
Mund Kiefer Gesichtschir. 1997 May;1(3):133-6. doi: 10.1007/BF03043532.
Expression of proliferation markers PCNA and MIB 1 was evaluated in 17 verrucous carcinomas and in five cases of normal squamous epithelium of the oral cavity. Immunohistochemistry revealed no significant differences in the proliferative activities. Highest expression was seen in the basal zones. Proliferative activity in more than 26% of cells is no longer compatible with verrucous carcinoma, but favours the diagnosis of squamous cell carcinoma.
在17例疣状癌和5例口腔正常鳞状上皮中评估增殖标志物PCNA和MIB 1的表达。免疫组织化学显示增殖活性无显著差异。最高表达见于基底区。超过26%的细胞增殖活性不再符合疣状癌，但支持鳞状细胞癌的诊断。
