Awange D O, Onyango J F
Department of Dental Surgery, College of Health Sciences, University of Nairobi, Kenya.
East Afr Med J. 1993 May;70(5):316-8.
Verrucous carcinoma is a rare and distinct pathological and clinical variant of well-differentiated squamous cell carcinoma. Two case reports of histologically proven oral verrucous carcinoma are presented. One case presented with a history of tobacco chewing, snuff taking and miraa chewing. While the relationship between tobacco chewing or snuff dipping and verrucous carcinoma has been investigated and described, the role played by miraa chewing is still unknown and thus requires further study. Both cases were successfully managed by only conservative surgical excision. No radiotherapy was used. Clinical and histo-pathological examination of verrucous carcinoma is therefore very important in its diagnosis and treatment planning.
疣状癌是一种罕见且独特的高分化鳞状细胞癌的病理和临床变体。本文报告2例经组织学证实的口腔疣状癌病例。1例患者有嚼烟、吸鼻烟和嚼阿拉伯茶的病史。虽然嚼烟或蘸鼻烟与疣状癌之间的关系已得到研究和描述，但嚼阿拉伯茶所起的作用仍不明确，因此需要进一步研究。2例均仅通过保守手术切除成功治愈，未进行放疗。因此，疣状癌的临床和组织病理学检查对其诊断和治疗规划非常重要。
