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电磁头颈热疗施加器:实验体模验证与有限时域差分模型

Electromagnetic head-and-neck hyperthermia applicator: experimental phantom verification and FDTD model.

作者信息

Paulides Margarethus M, Bakker Jurriaan F, van Rhoon Gerard C

机构信息

Department of Radiation Oncology, Section of Hyperthermia, Daniel den Hoed Cancer Center, Erasmus Medical Center, Rotterdam, The Netherlands.

出版信息

Int J Radiat Oncol Biol Phys. 2007 Jun 1;68(2):612-20. doi: 10.1016/j.ijrobp.2007.01.035. Epub 2007 Apr 9.

Abstract

PURPOSE

To experimentally verify the feasibility of focused heating in the neck region by an array of two rings of six electromagnetic antennas. We also measured the dynamic specific absorption rate (SAR) steering possibilities of this setup and compared these SAR patterns to simulations.

METHODS AND MATERIALS

Using a specially constructed laboratory prototype head-and-neck applicator, including a neck-mimicking cylindrical muscle phantom, we performed SAR measurements by electric field, Schottky-diode sheet measurements and, using the power-pulse technique, by fiberoptic thermometry and infrared thermography. Using phase steering, we also steered the SAR distribution in radial and axial directions. All measured distributions were compared with the predictions by a finite-difference time-domain-based electromagnetic simulator.

RESULTS

A central 50% iso-SAR focus of 35 +/- 3 mm in diameter and about 100 +/- 15 mm in length was obtained for all investigated settings. Furthermore, this SAR focus could be steered toward the desired location in the radial and axial directions with an accuracy of approximately 5 mm. The SAR distributions as measured by all three experimental methods were well predicted by the simulations.

CONCLUSION

The results of our study have shown that focused heating in the neck is feasible and that this focus can be effectively steered in the radial and axial directions. For quality assurance measurements, we believe that the Schottky-diode sheet provides the best compromise among effort, speed, and accuracy, although a more specific and improved design is warranted.

摘要

目的

通过由两圈各六个电磁天线组成的阵列,对颈部区域聚焦加热的可行性进行实验验证。我们还测量了该装置动态比吸收率(SAR)的控制可能性,并将这些SAR模式与模拟结果进行比较。

方法和材料

使用一个专门构建的实验室原型头颈施源器,包括一个模拟颈部的圆柱形肌肉模型,我们通过电场、肖特基二极管片测量以及使用功率脉冲技术,通过光纤温度测量法和红外热成像法进行SAR测量。利用相位控制,我们还在径向和轴向上控制了SAR分布。所有测量的分布都与基于时域有限差分的电磁模拟器的预测结果进行了比较。

结果

对于所有研究的设置,均获得了一个直径为35±3毫米、长度约为100±15毫米的中心50%等SAR焦点。此外,该SAR焦点可以在径向和轴向上以约5毫米的精度控制到所需位置。模拟结果很好地预测了所有三种实验方法测量的SAR分布。

结论

我们的研究结果表明,颈部聚焦加热是可行的,并且该焦点可以在径向和轴向上有效控制。对于质量保证测量,我们认为肖特基二极管片在工作量、速度和准确性之间提供了最佳折衷,尽管需要更具体和改进的设计。

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