Sidorov E V, Townson A F, Dvorak M F, Kwon B K, Steeves J, Krassioukov A
ICORD, University of British Columbia, Vancouver, British Columbia, Canada.
Spinal Cord. 2008 Jan;46(1):65-9. doi: 10.1038/sj.sc.3102064. Epub 2007 Apr 10.
Retrospective data analysis.
To determine prevalence of orthostatic hypotension (OH) in patients with spinal cord injury (SCI) during the acute rehabilitation period.
Quaternary care spinal unit, Vancouver General Hospital, British Columbia, Canada.
Eighty-nine patients with acute SCI stratified by neurological level (cervical, 55 (62%); upper thoracic, 12 (13%); lower thoracic, 22 (25%)), and graded by American Spinal Injury Association standards. Non-invasive measurement of systolic and diastolic blood pressure and heart rate were made at baseline and 3 min following an orthostatic challenge test administered during the first month after SCI.
Patients with cervical or upper thoracic motor complete SCI more frequently experienced OH (P<0.01). OH persisted during the first month following SCI in 74% of cervical and only 20% of upper thoracic motor complete SCI patients.
Patients with cervical and upper thoracic motor complete SCI are more likely to experience persistent OH than those with lower level or motor incomplete SCI during the first month of rehabilitation.
回顾性数据分析。
确定脊髓损伤（SCI）患者在急性康复期直立性低血压（OH）的患病率。
加拿大不列颠哥伦比亚省温哥华总医院四级护理脊髓科。
89例急性SCI患者按神经损伤平面分层（颈髓损伤，55例（62%）；胸髓上段损伤，12例（13%）；胸髓下段损伤，22例（25%）），并根据美国脊髓损伤协会标准进行分级。在SCI后第一个月内进行直立性挑战试验，分别于基线及试验后3分钟无创测量收缩压、舒张压和心率。
颈髓或胸髓上段运动完全性SCI患者发生OH的频率更高（P<0.01）。在SCI后的第一个月内，74%的颈髓运动完全性SCI患者OH持续存在，而胸髓上段运动完全性SCI患者仅为20%。
在康复的第一个月内，颈髓和胸髓上段运动完全性SCI患者比损伤平面较低或运动不完全性SCI患者更易发生持续性OH。
