Dion W M
Can Vet J. 1982 Sep;23(9):272-5.
The occurrence of protothecosis in a dairy herd quarantined under the National Brucellosis Eradication Program is reported. Infection was detected by milk culture and the presence of serum precipitins to a culture filtrate antigen preparation of Prototheca zopfi. The alga was always cultured from the milk when serum precipitins were present. Whey antibodies were demonstrated in infected quarters. Consumption of colostrum from an infected cow may have accounted for the brief appearance of serum precipitins in young calves. A naturally infected cow was monitored for 20 months. Serum antibodies disappeared six months after lactation ended but reappeared following parturition, with both algal cells and antibodies in the colostrum. Prototheca zopfi survived a 13 month dry period. There was no spread of infection to the calf. An experimental infection of a healthy cow was short lived but the presence of both serum and whey antibodies was demonstrated. Cross-reactions between Prototheca and Brucella abortus antigens were not observed, and the association between the diseases was found to be coincidental.
报告了在国家布鲁氏菌病根除计划下被隔离的奶牛群中发生原壁菌病的情况。通过乳汁培养以及针对佐氏原壁菌培养滤液抗原制剂的血清沉淀素的存在来检测感染。当存在血清沉淀素时，总能从乳汁中培养出该藻类。在受感染的乳腺中检测到了乳清抗体。饮用受感染母牛的初乳可能是幼犊血清沉淀素短暂出现的原因。对一头自然感染的母牛进行了20个月的监测。血清抗体在泌乳结束6个月后消失，但在分娩后再次出现，初乳中同时存在藻类细胞和抗体。佐氏原壁菌在13个月的干奶期存活下来。感染未传播给犊牛。对一头健康母牛进行的实验性感染持续时间较短，但证明了血清和乳清抗体的存在。未观察到原壁菌与流产布鲁氏菌抗原之间的交叉反应，发现这两种疾病之间的关联是巧合。
