Bosu W T, McKinnon A O
Can Vet J. 1982 Dec;23(12):358-60.
Four standardbred mares, 99 to 153 days pregnant, were treated with a synthetic prostaglandin analogue, prostalene, in an attempt to induce abortion. The mares received subcutaneous injection of either 2 mg prostalene (recommended luteolytic dose); 4 mg prostalene (double luteolytic dose) or 4 mg twice at intervals of 12 hours or 24 hours. The prostalene treatment resulted in cervical relaxation, increased tone of the uterus and decreased plasma concentrations of progesterone. None of the pregnant mares aborted within seven days after the first prostalene treatment. Abortions were subsequently induced by single or multiple intrauterine infusions using warm hypertonic saline. There were no postabortion complications.
四匹怀孕99至153天的标准bred母马接受了合成前列腺素类似物prostalene的治疗，试图诱导流产。母马皮下注射2毫克prostalene（推荐的溶黄体剂量）、4毫克prostalene（双倍溶黄体剂量），或4毫克，每隔12小时或24小时注射一次。prostalene治疗导致宫颈松弛、子宫张力增加和血浆孕酮浓度降低。在首次prostalene治疗后的七天内，没有一匹怀孕母马流产。随后通过单次或多次子宫内注入温热的高渗盐水诱导流产。流产后没有并发症。
