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肺脓肿:睾丸畸胎瘤治疗的致命并发症。

Lung abscess: a fatal complication of treatment for testicular teratoma.

作者信息

Senan I S, Kaye S B

机构信息

Beatson Oncology Centre, Western Infirmary, Glasgow, UK.

出版信息

Clin Oncol (R Coll Radiol). 1991 Nov;3(6):345-7. doi: 10.1016/s0936-6555(05)80591-6.

Abstract

We describe a patient with widely metastatic testicular teratoma who responded to intensive combination chemotherapy but developed a lung abscess in a necrotic tumour cavity, leading to death before surgical resection of residual lesions could take place. Post-mortem examination revealed necrotic tissue and mature differentiated teratoma, with no evidence of frank malignancy. This complication has not been previously reported in treated teratoma. Resolution of an abscess developing in a pre-existing thick-walled lesion is less likely with antibiotics alone. Awareness of this might salvage potentially curable cases by earlier surgical intervention.

摘要

我们描述了一名患有广泛转移的睾丸畸胎瘤患者,该患者对强化联合化疗有反应,但在坏死的肿瘤腔内形成了肺脓肿,导致在能够对残留病灶进行手术切除之前死亡。尸检显示为坏死组织和成熟分化的畸胎瘤,未发现明显恶性肿瘤的证据。这种并发症在既往接受治疗的畸胎瘤中尚未见报道。仅使用抗生素不太可能使在预先存在的厚壁病灶中形成的脓肿消退。认识到这一点可能通过早期手术干预挽救潜在可治愈的病例。

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