马麻醉后低氧血症的缓解
Alleviation of postanesthetic hypoxemia in the horse.
作者信息
McMurphy R M, Cribb P H
出版信息
Can Vet J. 1989 Jan;30(1):37-41.
This study was designed to investigate the effect of the nasotracheal insufflation of oxygen at a flow rate of 15 L/min on the arterial partial pressure of oxygen during the recovery period following inhalation anesthesia in the horse. It has been stated that this is a suitable flow rate to prevent postoperative hypoxemia but without any experimental evidence to support those statements. Horses being used for the study of healing of cartilage were anesthetized on two separate occasions. Following one period of anesthesia they were allowed to recover breathing room air, and following the other period of anesthesia oxygen was insufflated into the trachea at 15 L/min throughout the recovery period. This permitted each horse to act as its own control and allowed statistical analysis using Student's t-test for paired samples.The insufflated horses had a higher arterial partial pressure of oxygen during the recovery period than did the noninsufflated horses (p < 0.05).
本研究旨在调查以15升/分钟的流速经鼻气管吹入氧气对马吸入麻醉恢复期动脉血氧分压的影响。据称，这是预防术后低氧血症的合适流速，但尚无任何实验证据支持这些说法。用于软骨愈合研究的马匹在两个不同的时间点接受麻醉。在一段麻醉期后，让它们恢复呼吸室内空气，在另一段麻醉期后，在整个恢复期以15升/分钟的流速向气管内吹入氧气。这使得每匹马都能作为自身的对照，并允许使用配对样本的学生t检验进行统计分析。在恢复期，吹入氧气的马匹比未吹入氧气的马匹具有更高的动脉血氧分压（p < 0.05）。
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