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Isoflurane as an inhalational anesthetic agent in clinical practice.异氟烷作为临床实践中的吸入性麻醉剂。
Can Vet J. 1990 Dec;31(12):847-50.
2
Equi-MAC concentrations of halothane and isoflurane do not produce similar bispectral index values.相同最低肺泡有效浓度的氟烷和异氟烷并不会产生相似的脑电双频指数值。
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本文引用的文献

1
Comparison of circulatory and respiratory effects of isoflurane and halothane anesthesia in horses.异氟烷和氟烷麻醉对马循环和呼吸影响的比较。
Am J Vet Res. 1980 May;41(5):821-5.
2
Accuracy of isoflurane delivery by halothane-specific vaporizers.氟烷专用蒸发器输送异氟烷的准确性。
Am J Vet Res. 1983 Jun;44(6):1072-8.
3
Change of inhalation anesthetic agents for management of ventricular premature depolarizations in anesthetized cats and dogs.
J Am Vet Med Assoc. 1984 Sep 15;185(6):643-6.
4
Minimum alveolar anesthetic concentration: a standard of anesthetic potency.最低肺泡有效浓度:麻醉效能的一项标准。
Anesthesiology. 1965 Nov-Dec;26(6):756-63. doi: 10.1097/00000542-196511000-00010.
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Comparison of the arrhythmic doses of epinephrine during Forane, halothane, and fluroxene anesthesia in dogs.
Anesthesiology. 1971 Jul;35(1):48-53. doi: 10.1097/00000542-197107000-00015.
6
Skeletal muscle perfusion during prolonged 2.03% end-tidal isoflurane-O2 anesthesia in isocapnic ponies.等容性小马在持续吸入2.03%呼气末异氟烷-O₂麻醉期间的骨骼肌灌注情况。
Am J Vet Res. 1987 Jun;48(6):946-51.
7
Isoflurane anesthesia for equine colic surgery. Comparison with halothane anesthesia.
Vet Surg. 1987 Mar-Apr;16(2):184-8. doi: 10.1111/j.1532-950x.1987.tb00935.x.
8
Anaesthetic uptake and elimination: is there a difference between halothane and isoflurane in the dog?
Br J Anaesth. 1988 Mar;60(4):395-401. doi: 10.1093/bja/60.4.395.
9
Measurements of muscular microcirculation by laser Doppler flowmetry in isoflurane and halothane anaesthetised horses.
Vet Rec. 1987 Oct 3;121(14):324-6. doi: 10.1136/vr.121.14.324.
10
Effects of halothane and isoflurane on mean arterial blood pressure, heart rate, and respiratory rate in adult Pekin ducks.氟烷和异氟烷对成年北京鸭平均动脉血压、心率及呼吸频率的影响。
Am J Vet Res. 1990 Mar;51(3):458-60.

异氟烷作为临床实践中的吸入性麻醉剂。

Isoflurane as an inhalational anesthetic agent in clinical practice.

作者信息

Dohoo S E

出版信息

Can Vet J. 1990 Dec;31(12):847-50.

PMID:17423714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1480897/
Abstract

Isoflurane is the most recently available inhalational anesthetic agent on the market today. Although there have been few clinical trials comparing its use to halothane and methoxyflurane, the pharmacology of the agent suggests certain situations in which it may be the preferable agent. These include avian anesthesia, geriatric patients, patients with cardiovascular disease or hepatic disease, critically ill and unstable patients, cases such as brachiocephalics where upper airway obstruction is a concern during recovery, patients where increases in intracranial pressure should be avoided, and cesarean section. In addition, the rapid recoveries seen with isoflurane may be an advantage for outpatient surgeries.

摘要

异氟烷是目前市面上最新可用的吸入性麻醉剂。尽管将其与氟烷和甲氧氟烷进行比较的临床试验较少,但该药物的药理学表明在某些情况下它可能是更合适的药物。这些情况包括禽类麻醉、老年患者、患有心血管疾病或肝脏疾病的患者、重症和不稳定患者、在恢复过程中需要关注上呼吸道梗阻的病例(如短头畸形患者)、应避免颅内压升高的患者以及剖宫产手术。此外,异氟烷带来的快速恢复对于门诊手术可能是一个优势。